HSD17B14 and CA8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HSD17B14	CA8
Gene Name		hydroxysteroid (17-beta) dehydrogenase 14	carbonic anhydrase VIII
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	Steroid Catabolic Process Oxidation-reduction Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways
Drugs
Diseases
GWAS			Cardiac hypertrophy ( 21348951) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-Protein Interactions		15 interactors: CA8 CDKN2D DDIT3 LINC00152 MIR4435-1HG MPG NEK6 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B WDYHV1	9 interactors: CRX GGA2 HSD17B14 ITPR1 LNX1 LRCH4 MAGED1 SPDL1 TBX3
Entrez ID		51171	767
HPRD ID		16801	00266
Ensembl ID		ENSG00000087076
Uniprot IDs		Q9BPX1	P35219
PDB IDs		1YDE	2W2J
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus Deoxyribose Phosphate Catabolic Process Cellular Response To Stress Deoxyribonucleotide Catabolic Process Purine Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Deoxyribonucleotide Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Determination Of Dorsal Identity GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Nucleotide Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Depurination Negative Regulation Of Cell Cycle Programmed Cell Death Cell Cycle Process Cell Death Death MRNA 5'-splice Site Recognition Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Cellular Protein Metabolic Process Cell Cycle Arrest Organophosphate Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway DNA Damage Checkpoint Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process G1/S Transition Of Mitotic Cell Cycle DNA Dealkylation Involved In DNA Repair Autophagic Cell Death Base-excision Repair, AP Site Formation Ribonucleoside Diphosphate Catabolic Process Regulation Of Protein Metabolic Process Nucleoside Diphosphate Catabolic Process Cell Cycle Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteolysis SnRNA Transcription ER Overload Response Mitotic Cell Cycle Process Response To Stress	Atrioventricular Bundle Cell Differentiation Follicle-stimulating Hormone Secretion Positive Regulation Of Photoreceptor Cell Differentiation
Tagcloud ?			a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl
Tagcloud (Difference) ?			a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl
Tagcloud (Intersection) ?