PHF1 and AVPI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHF1	AVPI1
Description		PHD finger protein 1	arginine vasopressin induced 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton ESC/E(Z) Complex Site Of Double-strand Break
	Molecular Function	Transcription Corepressor Binding DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Histone Methyltransferase Binding	Protein Binding
	Biological Process	Chromatin Organization DNA Damage Response Negative Regulation Of Gene Expression, Epigenetic DNA Repair-dependent Chromatin Remodeling	Positive Regulation Of MAPK Cascade
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Refractive error ( 32231278)
Interacting Genes		77 interacting genes: ABI2 ARID5A ARRDC3 ATXN7L1 AVPI1 BHLHE40 BIRC7 BOLL CALCOCO2 CSTPP1 DISC1 DPF1 DYSF EFHC2 EZH2 FHL2 FOSB GOLGA6L9 GPKOW GPRASP3 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HOMEZ HSD17B14 INCA1 IRAK1BP1 KIAA0408 KRT40 LBX1 LZTS2 MAGED1 MDFI MEOX2 MORN3 NAB2 NEK6 PATZ1 PDLIM7 PFDN5 PIBF1 PRR20A PRR20B PRR20C PRR20D PRR20E RBBP8NL RBPMS SMG9 SORBS3 SPAG8 TFCP2 TFIP11 THAP1 TLE5 TNS2 TOX2 TP53BP2 TRIM23 USP54 VAC14 ZBTB10 ZBTB16 ZIM2 ZNF500 ZNF526 ZNF688 ZNF71 ZRANB1 ZSCAN32	34 interacting genes: AIRIM APP CABP2 CDCA7L CYSRT1 DGCR6L EMD ENKD1 GOLGA6L9 IKBKG KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP4-2 LMO3 LONRF1 MDFI MKRN3 PHF1 PICK1 POLR1C PPP1R16A PRKAA2 PRKACA PRKACB RIPPLY1 RIPPLY2 SCNM1
Entrez ID		5252	60370
HPRD ID		04195	16530
Ensembl ID		ENSG00000112511	ENSG00000119986
Uniprot IDs		A0A140VJR4 A0A1U9X8A3 O43189	Q5T686
PDB IDs		2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP 6WAT 6WAV 7LKY 8H43
Enriched GO Terms of Interacting Partners?		Nucleosome Assembly Structural Constituent Of Chromatin Nucleosome Organization Telomere Organization Nucleosome Protein-DNA Complex Assembly Nucleus DNA Binding Protein Heterodimerization Activity Chromosome Organization Epigenetic Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein-containing Complex Protein Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Gene Expression Chromatin Remodeling Cadherin Binding Identical Protein Binding Regulation Of Transcription By RNA Polymerase II Chromosome Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Transcription Factor Binding Nucleoplasm Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Corepressor Activity Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Transcription Corepressor Binding Protein-containing Complex Assembly Protein-containing Complex Organization	Keratin Filament Intermediate Filament Protein Localization To Lipid Droplet Cytosol CAMP-dependent Protein Kinase Activity Regulation Of Glycolytic Process CAMP-dependent Protein Kinase Complex Ciliary Base High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Somite Rostral/caudal Axis Specification Nucleotide-activated Protein Kinase Complex Regulation Of Carbohydrate Catabolic Process Negative Regulation Of TORC1 Signaling TORC1 Signaling Vascular Endothelial Cell Response To Fluid Shear Stress Regulation Of ATP Metabolic Process Axis Specification Regulation Of Purine Nucleotide Metabolic Process TOR Signaling Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis Positive Regulation Of Protein Export From Nucleus Negative Regulation Of TOR Signaling Positive Regulation Of Glycolytic Process Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Regulation Of TORC1 Signaling Protein-lipid Complex Assembly Positive Regulation Of Receptor Internalization Protein Serine/threonine/tyrosine Kinase Activity Multicellular Organismal-level Water Homeostasis Amyloid Fibril Formation Cellular Response To Nutrient Levels Embryonic Axis Specification Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Identical Protein Binding TMEM240-body Cellular Response To Fluid Shear Stress Negative Regulation Of Signaling Negative Regulation Of Cell Communication
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