FATE1 and CREB3L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FATE1	CREB3L3
Description		fetal and adult testis expressed 1	cAMP responsive element binding protein 3 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	Golgi Membrane Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Positive Regulation Of Acute Inflammatory Response Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription By RNA Polymerase II
Pathways			CREB3 factors activate genes Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Systemising ( 31508503)	Apolipoprotein A1 levels ( 32203549) Triglyceride levels ( 32203549)
Interacting Genes		99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1	30 interacting genes: ATF6 BAD CEBPG CEP19 CREB3 CREB3L1 CSNK2A1 CYB561A3 DPY30 FATE1 GPR25 GSK3B KHDRBS1 KPNA2 MCRS1 MS4A13 PELI2 RHAG RIOK3 RUSF1 SGTA SGTB SLC38A7 SLC39A9 STX5 TCEANC TMEM239 TRAF3IP3 USP7 YIPF6
Entrez ID		89885	84699
HPRD ID		02346	16752
Ensembl ID		ENSG00000147378	ENSG00000060566
Uniprot IDs		Q969F0	Q68CJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding	Regulation Of Cellular Response To Stress Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process TRC Complex Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Autophagy Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Catabolic Process Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Proteolysis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Stress Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Autophagy Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Unfolded Protein Positive Regulation Of Type I Interferon Production Regulation Of Apoptotic Signaling Pathway Identical Protein Binding Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Intracellular Signal Transduction Poly(U) RNA Binding Protein Binding Negative Regulation Of Apoptotic Signaling Pathway Golgi Membrane Membrane Protein Targeting To ER Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Macromolecule Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of DNA Metabolic Process RNA Polymerase II Transcription Regulator Complex Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ER-nucleus Signaling Pathway Regulation Of Microtubule Anchoring At Centrosome Regulation Of Type I Interferon Production Golgi Apparatus Methylammonium Transmembrane Transporter Activity
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