FATE1 and SYNGR2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		FATE1	SYNGR2
Description		fetal and adult testis expressed 1	synaptogyrin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	Lipid Droplet Synaptic Vesicle Membrane Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuromuscular Junction Synapse Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Regulated Exocytosis Synaptic Vesicle Membrane Organization
Pathways
Drugs
Diseases
GWAS		Systemising ( 31508503)	Adenocarcinoma ( 26732429) Lung cancer ( 26732429) Red blood cell count ( 32888494)
Interacting Genes		99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1	9 interacting genes: BDKRB2 C5AR2 CCR4 DRD2 F2RL1 FATE1 GPR35 LTB4R2 SCARA3
Entrez ID		89885	9144
HPRD ID		02346	04891
Ensembl ID		ENSG00000147378	ENSG00000108639
Uniprot IDs		Q969F0	O43760
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding	G Protein-coupled Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration G Protein-coupled Receptor Signaling Pathway Interneuron Migration Arachidonate Secretion Chemokine Receptor Activity Inflammatory Response G-protein Alpha-subunit Binding Negative Regulation Of Insulin Secretion Membrane Negative Regulation Of Peptide Secretion Long-chain Fatty Acid Transport Vasodilation Smooth Muscle Contraction Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Chemotaxis Negative Regulation Of Hormone Secretion Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Regulation Of Biological Quality Locomotion Negative Regulation Of Protein Secretion Cell Migration Chemokine-mediated Signaling Pathway Bradykinin Receptor Activity Fatty Acid Transport G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Proteinase-activated Receptor Activity Regulation Of Interleukin-8 Production Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Leukotriene B4 Receptor Activity Protease Binding Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Cell Motility Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Negative Regulation Of Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Complement Component C5a Receptor Activity Leukotriene Receptor Activity Renal System Process
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