FATE1 and TIMMDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FATE1	TIMMDC1
Description		fetal and adult testis expressed 1	translocase of inner mitochondrial membrane domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Mitochondrial Respiratory Chain Complex I Assembly
Pathways			Complex I biogenesis
Drugs
Diseases
GWAS		Systemising ( 31508503)	Autoimmune thyroid disease ( 32581359) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602 31604244) Primary biliary cholangitis ( 30643196) Primary biliary cirrhosis ( 22961000) Systemic lupus erythematosus ( 28714469 33272962) Systemic sclerosis ( 31672989)
Interacting Genes		99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1	82 interacting genes: AGR3 ANKRD46 APOC2 APOC4 APOL2 APOL3 APP ARL6IP6 ARLN ATP6AP2 BCAP31 C14orf180 C3orf52 C5orf46 CCL4 CDS2 CMTM2 CREB3L1 CYB561D2 CYP4F12 DCBLD2 DIABLO DRAM1 EPGN FAM20B FAM210B FATE1 FXYD3 GJB2 GPR151 GPR152 GPX8 HGS HSD17B13 IFNA2 IGFBP5 KIR2DL4 LHFPL5 MARCHF5 NDUFB11 NINJ1 ORMDL1 ORMDL2 PEX16 PEX5 PIGF PTPN1 PTPRN REEP6 RNF24 SCAMP5 SCD SERF1A SERF1B SERP1 SERP2 SLC35E4 SLC35F6 SLC61A1 SLC71A2 SMO ST6GAL2 STX12 STX6 TMEM144 TMEM14B TMEM176A TMEM203 TMEM239 TMEM31 TMEM54 TMEM65 TMEM86A TVP23B UBIAD1 UNC50 UNC93A VAPB VMA12 YIF1A YIPF1 YIPF4
Entrez ID		89885	51300
HPRD ID		02346	12817
Ensembl ID		ENSG00000147378	ENSG00000113845
Uniprot IDs		Q969F0	C9JU35 Q9NPL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipoprotein Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Golgi Membrane Response To Unfolded Protein Very-low-density Lipoprotein Particle Golgi Apparatus Response To Endoplasmic Reticulum Stress High-density Lipoprotein Particle Chemical Homeostasis Intermediate-density Lipoprotein Particle Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Amyloid Fibril Formation Protein Import Into Peroxisome Membrane Negative Regulation Of Sphingolipid Biosynthetic Process Menaquinone Metabolic Process Synaptic Vesicle Membrane Serine Palmitoyltransferase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment
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