SRRT and CHD3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SRRT	CHD3
Gene Name		serrate, RNA effector molecule	chromodomain helicase DNA binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Protein Binding Poly(A) RNA Binding	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Primary MiRNA Processing Response To Arsenic-containing Substance Neuronal Stem Cell Maintenance	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS		Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions		12 interactors: APP CHD3 CSNK2A1 GEMIN4 GIT1 HNRNPK HSPA8 IMMT SNRPF STAT3 VAV2 VIM	90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1
Entrez ID		51593	1107
HPRD ID		10665	09071
Ensembl ID		ENSG00000087087	ENSG00000170004
Uniprot IDs		Q9BXP5	B3KWV4 Q12873 Q2TAZ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Guidance MRNA Processing Movement Of Cell Or Subcellular Component Generation Of Neurons Axonogenesis MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neurogenesis Axon Development RNA Processing Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Differentiation Cell Development Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation RNA Splicing Neuron Projection Development RNA Metabolic Process Cell Projection Morphogenesis Nervous System Development Cell Part Morphogenesis Positive Regulation Of Metabolic Process Gene Expression Neuron Development Cell Morphogenesis Viral Process Cell Projection Organization Astrocyte Differentiation Spliceosomal SnRNP Assembly Locomotion Chaperone-mediated Protein Folding Negative Regulation Of Neurogenesis Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Cell Differentiation Negative Regulation Of Fibril Organization Negative Regulation Of Cell Development RNA Biosynthetic Process Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter	Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process
Tagcloud ?		4s abnormally biotic bipolar brodmann clique cliques devastating distinctive epidemiologic housekeeping interconnected interconnecting knitted module postmortem ppi prefrontal proteomics sbno2 schizophrenia sec24c shared shocks switchboard topological ubc unidentified ywhaz	ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous
Tagcloud (Difference) ?		4s abnormally biotic bipolar brodmann clique cliques devastating distinctive epidemiologic housekeeping interconnected interconnecting knitted module postmortem ppi prefrontal proteomics sbno2 schizophrenia sec24c shared shocks switchboard topological ubc unidentified ywhaz	ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous
Tagcloud (Intersection) ?