SRRT and HNRNPK

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SRRT	HNRNPK
Gene Name		serrate, RNA effector molecule	heterogeneous nuclear ribonucleoprotein K
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Membrane Cell Projection Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Protein Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Primary MiRNA Processing Response To Arsenic-containing Substance Neuronal Stem Cell Maintenance	MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Processing Signal Transduction RNA Splicing Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions		12 interactors: APP CHD3 CSNK2A1 GEMIN4 GIT1 HNRNPK HSPA8 IMMT SNRPF STAT3 VAV2 VIM	107 interactors: ABI2 APBB1 AQP5 BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FYN GFI1B GRAP2 GRB2 GZMA GZMK HCK HIST3H3 HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 PTBP1 QKI RALY RASD1 RBFOX2 RBM10 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18S5 RNA28S5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRRT SRSF3 SUMO1 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 U2AF2 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF792 ZNRF2P1
Entrez ID		51593	3190
HPRD ID		10665	02834
Ensembl ID		ENSG00000087087	ENSG00000165119
Uniprot IDs		Q9BXP5	B4DFF1 B4DUQ1 P61978 Q6IBN1
PDB IDs			1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?		Axon Guidance MRNA Processing Movement Of Cell Or Subcellular Component Generation Of Neurons Axonogenesis MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neurogenesis Axon Development RNA Processing Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Differentiation Cell Development Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation RNA Splicing Neuron Projection Development RNA Metabolic Process Cell Projection Morphogenesis Nervous System Development Cell Part Morphogenesis Positive Regulation Of Metabolic Process Gene Expression Neuron Development Cell Morphogenesis Viral Process Cell Projection Organization Astrocyte Differentiation Spliceosomal SnRNP Assembly Locomotion Chaperone-mediated Protein Folding Negative Regulation Of Neurogenesis Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Cell Differentiation Negative Regulation Of Fibril Organization Negative Regulation Of Cell Development RNA Biosynthetic Process Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Immune Response Positive Regulation Of Metabolic Process MRNA Stabilization Innate Immune Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Metabolic Process Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Immune System Process Positive Regulation Of Gene Expression Regulation Of Immune System Process Defense Response Fc Receptor Signaling Pathway Positive Regulation Of Signal Transduction T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		4s abnormally biotic bipolar brodmann clique cliques devastating distinctive epidemiologic housekeeping interconnected interconnecting knitted module postmortem ppi prefrontal proteomics sbno2 schizophrenia sec24c shared shocks switchboard topological ubc unidentified ywhaz	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Difference) ?		4s abnormally biotic bipolar brodmann clique cliques devastating distinctive epidemiologic housekeeping interconnected interconnecting knitted module postmortem ppi prefrontal proteomics sbno2 schizophrenia sec24c shared shocks switchboard topological ubc unidentified ywhaz	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Intersection) ?