SRRT and LINC00624

Number of citations of the paper that reports this interaction (PubMedID 32869873)
0

Data Source:
BioGRID (unspecified method)

		SRRT	LINC00624
Description		serrate, RNA effector molecule	long intergenic non-protein coding RNA 624
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body Protein-containing Complex Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Protein-macromolecule Adaptor Activity MRNA Cap Binding Complex Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulatory NcRNA-mediated Gene Silencing Primary MiRNA Processing Response To Arsenic-containing Substance Positive Regulation Of Neurogenesis Neuronal Stem Cell Population Maintenance
Pathways		RNA polymerase II transcribes snRNA genes mRNA Splicing - Major Pathway Nuclear RNA decay
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Hemoglobin levels ( 32327693) Liver enzyme levels (alkaline phosphatase) ( 33972514) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Resting heart rate ( 27798624) RR interval (heart rate) ( 30679814)	Body mass index and systolic blood pressure (bivariate analysis) ( 33539483) End-stage kidney disease ( 31178898) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		16 interacting genes: APP CACNA1C CHD3 CSNK2A1 GEMIN4 GIT1 HNRNPK HSPA8 HTR6 IMMT LINC00624 SNRPF STAT3 SUMO2 VAV2 VIM	38 interacting genes: ACTA1 ACTC1 ADAR ALB CCT2 CCT4 CPNE3 DDX42 DDX5 EIF2AK2 FUBP3 G6PD H2BC18 HDAC6 HNRNPL HNRNPM HNRNPU HRNR ILF3 MCCC1 MCCC2 NONO PARP1 PTBP1 PTBP2 PTBP3 SERBP1 SFPQ SND1 SRRT STAU1 STAU2 TRIM28 TUBA1B TUBA1C UBAP2L YBX3 ZNF354C
Entrez ID		51593	100289211
HPRD ID		10665
Ensembl ID		ENSG00000087087	ENSG00000278811
Uniprot IDs		Q9BXP5
PDB IDs		5OO6 6F7J 6F7P 6F7S 6F8D 8PMP
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Import Regulation Of Glycolytic Process MRNA Metabolic Process Regulation Of Carbohydrate Catabolic Process RNA Binding Negative Regulation Of Inflammatory Response To Wounding Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Inflammatory Response To Wounding Protein Targeting To Vacuole Involved In Autophagy Regulation Of Interleukin-1 Beta Production Small Nuclear Ribonucleoprotein Complex Positive Regulation Of Catabolic Process SMN-Sm Protein Complex Regulation Of Interleukin-1 Production PML Body Negative Regulation Of Glycolytic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of ATP Metabolic Process RNA Splicing Astrocyte Differentiation Positive Regulation Of ATP Metabolic Process Spliceosomal Complex Focal Adhesion MRNA Processing Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Dendrite Amylin Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Toll Signaling Pathway RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Chaperone-mediated Autophagy Translocation Complex Disassembly Spliceosomal SnRNP Assembly Negative Regulation Of ARF Protein Signal Transduction Protein Targeting To Vacuole Regulation Of Biological Quality RNA Metabolic Process Presynapse Postsynapse Regulation Of Cellular Response To Stress Positive Regulation Of Interleukin-1 Beta Production Acetylcholine Receptor Activator Activity Regulation Of Multicellular Organism Growth Lipoprotein Particle Positive Regulation Of Protein Import	RNA Binding RNA Localization Nucleic Acid Binding Double-stranded RNA Binding MRNA Processing MRNA Binding Negative Regulation Of Macromolecule Biosynthetic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Viral Genome Replication Negative Regulation Of Metabolic Process Dendritic Transport Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression RNA Splicing Regulation Of Viral Life Cycle RNA Processing Cytoskeleton-dependent Intracellular Transport Alternative MRNA Splicing, Via Spliceosome Regulation Of Viral Process RNA Metabolic Process Cell Body Nucleus Axo-dendritic Transport Paraspeckles Regulation Of Macromolecule Biosynthetic Process Intracellular MRNA Localization Extracellular Exosome Regulation Of RNA Splicing Methylcrotonoyl-CoA Carboxylase Complex Methylcrotonoyl-CoA Carboxylase Activity Regulation Of Telomere Maintenance Via Telomere Lengthening Pre-mRNA Binding Cytoplasm Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Dendritic Transport Of Messenger Ribonucleoprotein Complex Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Response To Chemical Stress Negative Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Regulatory NcRNA-mediated Gene Silencing Transport Along Microtubule Binding Of Sperm To Zona Pellucida Mesenchyme Migration ScaRNA Localization To Cajal Body
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