PDGFRB and JAK1

  • Number of citations of the paper that reports this interaction (PMID 8657151)
  • 43
  • Data Source:
  • HPRD (in vitro, in vivo)

PDGFRB

JAK1

Gene Name platelet-derived growth factor receptor, beta polypeptide Janus kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 59 interactors: ARAF BAG1 CAV1 CAV3 CBL COPA COPB1 CRK EGFR EIF2AK2 FYN GAB1 GRB10 GRB14 GRB2 GRB7 ITGB3 JAK1 JAK2 KLHL12 KRTAP4-12 NCK1 NCK2 NEDD4 PDAP1 PDGFB PDGFD PDGFRA PIK3C2B PIK3CA PIK3R1 PIK3R2 PIK3R3 PLCG1 PRDX2 PTK2 PTPN1 PTPN11 PTPN2 PTPRJ RAF1 RASA1 S1PR1 SHC1 SLC9A3R1 SNX1 SNX2 SNX4 SOCS1 SRC STAT1 STAT3 STAT5A STAT5B SYNGAP1 TRIP6 TYK2 VAV1 YES1 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2
Entrez ID 5159 3716
HPRD ID 01423 00992
Ensembl ID ENSG00000113721 ENSG00000162434
Uniprot IDs P09619 Q59F04 P23458
PDB IDs 1GQ5 1H9O 1LWP 2L6W 2PLD 2PLE 3MJG 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01
Enriched GO Terms of Interacting Partners?
Tagcloud ?
14q32  5q31  5q33  apart  apl  aspirate  break  complication  cytogenetic  cytogenetics  exon  firstly  fusion  infrequent  kiaa1509  myeloid  neoplasm  neoplasms  partner  promyelocytic  q32  q33  rara  rarely  rearrangement  rt  trip11  undetectable  xy 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Difference) ?
14q32  5q31  5q33  apart  apl  aspirate  break  complication  cytogenetic  cytogenetics  exon  firstly  fusion  infrequent  kiaa1509  myeloid  neoplasm  neoplasms  partner  promyelocytic  q32  q33  rara  rarely  rearrangement  rt  trip11  undetectable  xy 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Intersection) ?