PHF11 and AGPAT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PHF11	AGPAT2
Gene Name		PHD finger protein 11	1-acylglycerol-3-phosphate O-acyltransferase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Zinc Ion Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways			Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		5 interactors: AGPAT2 CSNK2B LSM8 MCPH1 PIAS4	6 interactors: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2
Entrez ID		51131	10555
HPRD ID		08480	04373
Ensembl ID		ENSG00000136147	ENSG00000169692
Uniprot IDs		Q9UIL8	O15120
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Chromosome Condensation Wnt Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Endothelial Tube Morphogenesis CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Protein Localization To Centrosome Positive Regulation Of Protein Sumoylation	Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Transepithelial L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Transport GMP Biosynthetic Process Nucleobase Transport Intestinal Cholesterol Absorption GMP Metabolic Process Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion L-ascorbic Acid Metabolic Process Transepithelial Transport Purine Nucleobase Biosynthetic Process Organic Anion Transport Vitamin Transmembrane Transport Response To Drug Intestinal Absorption Negative Regulation Of Lipid Transport Nucleobase-containing Compound Metabolic Process Cholesterol Efflux Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anion Transport Glutamine Metabolic Process Regulation Of Cholesterol Transport Small Molecule Metabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleobase Metabolic Process Vitamin Transport Excretion Nitrogen Compound Metabolic Process Carbohydrate Transmembrane Transport Pigment Biosynthetic Process Sterol Transport Cholesterol Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Carboxylic Acid Metabolic Process Water-soluble Vitamin Metabolic Process
Tagcloud ?		aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?