PHF11 and MCPH1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PHF11	MCPH1
Gene Name		PHD finger protein 11	microcephalin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Microtubule Organizing Center
	Molecular Function	Zinc Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle Cerebral Cortex Development
Pathways			Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)	Cytomegalovirus antibody response ( 21993531) Epirubicin-induced leukopenia ( 21799462)
Protein-Protein Interactions		5 interactors: AGPAT2 CSNK2B LSM8 MCPH1 PIAS4	9 interactors: ABCC2 CHEK1 H2AFX KDM1A MCM2 PHF11 SMARCB1 SMARCC2 TADA2A
Entrez ID		51131	79648
HPRD ID		08480	06174
Ensembl ID		ENSG00000136147	ENSG00000147316
Uniprot IDs		Q9UIL8	Q8NEM0
PDB IDs			2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Chromosome Condensation Wnt Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Endothelial Tube Morphogenesis CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Protein Localization To Centrosome Positive Regulation Of Protein Sumoylation	Chromatin Organization Chromosome Organization Nucleosome Organization Chromatin Assembly Or Disassembly Chromatin Modification Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Nucleosome Disassembly Nucleobase-containing Compound Metabolic Process Cell Cycle Process Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Remodeling Regulation Of Chromosome Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cell Cycle Nitrogen Compound Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Regulation Of DNA Repair ATP-dependent Chromatin Remodeling Histone Modification Biosynthetic Process Regulation Of Primitive Erythrocyte Differentiation DNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Response To Stress Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Prostaglandin Transport Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Histone H3-T11 Phosphorylation Transcription, DNA-templated Nucleosome Assembly RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Chromatin Assembly DNA Repair Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Protein-DNA Complex Assembly Positive Regulation Of Gene Expression
Tagcloud ?		aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal	8p23 aberrantly advance alleviated aneuploidy bona break breaks brit1 centrosome chromatid comet convincing doi dsb fide heterozygosity joining karyotyping lymphomas meanwhile mefs metaphase multiplication onc online publication reconstituted
Tagcloud (Difference) ?		aeroallergen allergen asthma asthmatic asthmatics atopy bronchodilator call caucasian eczema genotyped hardy helper homeodomain ige multiplex nineteen positional prick schools sensitization snapshot snps spirometric spirometry tagging weakly weinberg wheal	8p23 aberrantly advance alleviated aneuploidy bona break breaks brit1 centrosome chromatid comet convincing doi dsb fide heterozygosity joining karyotyping lymphomas meanwhile mefs metaphase multiplication onc online publication reconstituted
Tagcloud (Intersection) ?