SNX7 and MESDC2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SNX7	MESDC2
Gene Name		sorting nexin 7	mesoderm development candidate 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane	Cellular_component Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Molecular_function Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Endocytosis Protein Transport Vesicle Organization	Protein Folding Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Proinsulin levels ( 21873549)
Protein-Protein Interactions		7 interactors: BIRC3 HGS HMOX2 MAGEA11 MESDC2 POLR2L TEX11	9 interactors: APP ATP6V1E1 BRD4 KPNB1 LRP5 PSMA5 RFC3 SNX5 SNX7
Entrez ID		51375	23184
HPRD ID		15416	12129
Ensembl ID		ENSG00000162627	ENSG00000117899
Uniprot IDs		B4DP69 E9PNL2 Q9UNH6	Q14696
PDB IDs		3IQ2
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Endocytosis Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Synaptic Growth At Neuromuscular Junction Cell-cell Signaling Involved In Mammary Gland Development Cholesterol Metabolic Process Viral Process Positive Regulation Of Canonical Wnt Signaling Pathway Sterol Metabolic Process Homeostatic Process Collateral Sprouting In Absence Of Injury Protein Transport Vesicle-mediated Transport Transition Metal Ion Homeostasis Establishment Of Protein Localization Negative Regulation Of DNA Damage Checkpoint Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Histone H3-K14 Acetylation Positive Regulation Of Wnt Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Retinal Blood Vessel Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Cellular Homeostasis Extracellular Matrix-cell Signaling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glucose Catabolic Process Mitotic Cell Cycle Axon Choice Point Recognition Bone Marrow Development Negative Regulation Of Catalytic Activity Cellular Response To Stimulus Vesicle Organization Negative Regulation Of Cellular Protein Metabolic Process
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