VPS16 and HOOK2

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS16	HOOK2
Gene Name		vacuolar protein sorting 16 homolog (S. cerevisiae)	hook microtubule-tethering protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Late Endosome Actin Filament Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Centrosome Microtubule HOPS Complex FHF Complex
	Molecular Function	Actin Binding Actin Filament Binding	Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell	Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: AKTIP HOOK1 HOOK2 HOOK3 MON1B STX7 UVRAG VPS11 VPS18 VPS33A	31 interactors: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 CCDC33 CWF19L2 DUSP13 EPS8 FAM107A HOOK1 HOOK3 IQCE ITSN2 KANSL1 KAT7 KIAA0408 MCM10 PSMF1 RALBP1 RIBC2 SUV39H1 USP2 UTP14A UTP14C VPS16 VPS41 ZC2HC1C ZNF250 ZNF638
Entrez ID		64601	29911
HPRD ID		12259	09698
Ensembl ID		ENSG00000215305	ENSG00000095066
Uniprot IDs		Q9H269	Q96ED9
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?		Endosome Organization Vesicle-mediated Transport Lysosome Organization Early Endosome To Late Endosome Transport Vacuole Organization Endosome To Lysosome Transport Lysosomal Transport Protein Transport Establishment Of Protein Localization Vacuolar Transport Protein Localization Establishment Of Localization In Cell Transport Cellular Localization Intracellular Transport Endomembrane System Organization Endosomal Transport Vesicle Docking Membrane Docking Organelle Organization Viral Entry Into Host Cell Cytoplasmic Transport Entry Into Host Cell Vesicle Fusion Vesicle Docking Involved In Exocytosis Organelle Fusion Positive Regulation Of Receptor Localization To Synapse Organelle Localization Interaction With Host Membrane Fusion Cellular Protein Localization Viral Life Cycle Regulation Of SNARE Complex Assembly Vesicle Organization SNARE Complex Assembly Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Protein Localization To Centrosome Golgi Localization Interkinetic Nuclear Migration Exocytosis Protein Localization To Cytoskeleton Platelet Formation Platelet Morphogenesis Regulation Of Developmental Pigmentation Regulation Of Vesicle-mediated Transport Neuronal Stem Cell Maintenance Lysosome Localization Positive Regulation Of Autophagy	Early Endosome To Late Endosome Transport Vacuolar Transport Endosomal Transport Vacuole Organization Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Regulation Of SNARE Complex Assembly Lysosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Organelle Organization RRNA Processing RRNA Metabolic Process Maturation Of SSU-rRNA Cytoplasmic Transport Regulation Of Vesicle Fusion Ribosomal Small Subunit Biogenesis Ribosome Biogenesis Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Histone H4 Acetylation Peptidyl-lysine Modification Viral Process Protein Transport Actin Polymerization-dependent Cell Motility Vesicle-mediated Transport Establishment Of Protein Localization
Tagcloud ?		adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Difference) ?		adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Intersection) ?