VPS16 and UVRAG

Number of citations of the paper that reports this interaction (PMID 18552835)
136

Data Source:
BioGRID (affinity chromatography technology, imaging technique)
HPRD (in vivo)

		VPS16	UVRAG
Gene Name		vacuolar protein sorting 16 homolog (S. cerevisiae)	UV radiation resistance associated
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Late Endosome Actin Filament Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome	Cytoplasm Lysosome Early Endosome Late Endosome Protein Complex Phagocytic Vesicle
	Molecular Function	Actin Binding Actin Filament Binding	SNARE Binding Protein Binding SH3 Domain Binding
	Biological Process	Intracellular Protein Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell	DNA Repair Positive Regulation Of Autophagy SNARE Complex Assembly Viral Entry Into Host Cell Regulation Of Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: AKTIP HOOK1 HOOK2 HOOK3 MON1B STX7 UVRAG VPS11 VPS18 VPS33A	4 interactors: VPS11 VPS16 VPS18 VPS33B
Entrez ID		64601	7405
HPRD ID		12259	03929
Ensembl ID		ENSG00000215305
Uniprot IDs		Q9H269	Q9P2Y5
PDB IDs		4BX9
Enriched GO Terms of Interacting Partners?		Endosome Organization Vesicle-mediated Transport Lysosome Organization Early Endosome To Late Endosome Transport Vacuole Organization Endosome To Lysosome Transport Lysosomal Transport Protein Transport Establishment Of Protein Localization Vacuolar Transport Protein Localization Establishment Of Localization In Cell Transport Cellular Localization Intracellular Transport Endomembrane System Organization Endosomal Transport Vesicle Docking Membrane Docking Organelle Organization Viral Entry Into Host Cell Cytoplasmic Transport Entry Into Host Cell Vesicle Fusion Vesicle Docking Involved In Exocytosis Organelle Fusion Positive Regulation Of Receptor Localization To Synapse Organelle Localization Interaction With Host Membrane Fusion Cellular Protein Localization Viral Life Cycle Regulation Of SNARE Complex Assembly Vesicle Organization SNARE Complex Assembly Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Protein Localization To Centrosome Golgi Localization Interkinetic Nuclear Migration Exocytosis Protein Localization To Cytoskeleton Platelet Formation Platelet Morphogenesis Regulation Of Developmental Pigmentation Regulation Of Vesicle-mediated Transport Neuronal Stem Cell Maintenance Lysosome Localization Positive Regulation Of Autophagy	Regulation Of SNARE Complex Assembly Protein Transport Regulation Of Vesicle Fusion Establishment Of Protein Localization Viral Entry Into Host Cell Entry Into Host Cell Vesicle Docking Involved In Exocytosis Protein Localization Establishment Of Localization In Cell Vesicle Docking Membrane Docking Interaction With Host Cellular Localization Regulation Of Vacuole Fusion, Non-autophagic Intracellular Protein Transport Viral Life Cycle Cellular Protein Localization Vesicle-mediated Transport Platelet Alpha Granule Organization Intracellular Transport Regulation Of Protein Complex Assembly Exocytosis Regulation Of Vesicle-mediated Transport Endomembrane System Organization Transport Secretion By Cell Regulation Of Vacuole Organization Viral Process Secretion Endosome Organization Lysosome Localization Secretory Granule Organization Melanosome Localization Regulation Of Organelle Organization Lysosome Organization Cellular Pigmentation Locomotion Vacuole Organization Pigmentation Membrane Fusion Endosomal Transport Vesicle Organization Vesicle Localization Regulation Of Cellular Component Organization
Tagcloud ?		adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula	autophagy cd8 clearance conditional dampened defects deficient delayed embryonic encodes endocytic explained homeostasis homeostatic homozygous impaired insights instead knockout lacked lcmv lethality naive peripheral putative radiation regulator trafficking
Tagcloud (Difference) ?		adherens anxb9 apical appearance b9 basolateral boundary colocalizations coracle cytoskeleton destabilization disrupting dlg endosomal eps15 fidelity intimately karst multivesicular mvb pak redistribution segregation shotgun spectrin spliceoforms ubiquitylated vesicles zonula	autophagy cd8 clearance conditional dampened defects deficient delayed embryonic encodes endocytic explained homeostasis homeostatic homozygous impaired insights instead knockout lacked lcmv lethality naive peripheral putative radiation regulator trafficking
Tagcloud (Intersection) ?