PDCD2 and LSM8

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		PDCD2	LSM8
Gene Name		programmed cell death 2	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	DNA Binding Protein Binding Enzyme Binding Metal Ion Binding	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: HCFC1 LSM8 NCOR1 NFKBIB PARK2	49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		5134	51691
HPRD ID		02922	06288
Ensembl ID		ENSG00000071994
Uniprot IDs		E9PCU7 F5GYS7 Q16342	A4D0W0 O95777
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of JNK Cascade Negative Regulation Of Stress-activated MAPK Cascade RNA Metabolic Process Gene Expression Protein Stabilization Regulation Of Lipid Transport Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Nucleobase-containing Compound Metabolic Process Regulation Of Protein Stability Regulation Of Anion Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Release From Viral Latency Regulation Of Carbohydrate Metabolic Process Transcription, DNA-templated Negative Regulation Of MAPK Cascade Cellular Nitrogen Compound Metabolic Process Regulation Of JNK Cascade RNA Biosynthetic Process Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Regulation Of Stress-activated MAPK Cascade Nitrogen Compound Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Definitive Erythrocyte Differentiation Cellular Response To Manganese Ion Regulatory T Cell Differentiation Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Cellular Macromolecule Biosynthetic Process Aggresome Assembly Macromolecule Biosynthetic Process	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2
Tagcloud ?		aberrant aimed alters antitumor arrest atm blotting carcinogenesis chk1 conserved contribute gastric immunohistochemistry investigate line mkn28 mkn45 mutated nude p53 phase poor programmed qrt skin specimens suppressed ultraviolet uvb
Tagcloud (Difference) ?		aberrant aimed alters antitumor arrest atm blotting carcinogenesis chk1 conserved contribute gastric immunohistochemistry investigate line mkn28 mkn45 mutated nude p53 phase poor programmed qrt skin specimens suppressed ultraviolet uvb
Tagcloud (Intersection) ?