PDCD2

Description		programmed cell death 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Enzyme Binding Metal Ion Binding
	Biological Process	Apoptotic Process Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
Interacting Genes		7 interacting genes: ERRFI1 HCFC1 LSM8 NCOR1 NFKBIB PRKN TBC1D21
Entrez ID		5134
HPRD ID		02922
Ensembl ID		ENSG00000071994
Uniprot IDs		A0A087WYJ3 F5H4V9 J3QK82 Q16342
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MAPK Cascade Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of JNK Cascade Regulation Of Phosphorus Metabolic Process Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Regulation Of ATP Metabolic Process Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Protein Catabolic Process At Presynapse Response To Glucocorticoid Negative Regulation Of Intralumenal Vesicle Formation Negative Regulation Of Kinase Activity Regulation Of Purine Nucleotide Metabolic Process Mitochondrion To Lysosome Vesicle-mediated Transport Mitochondrion-derived Vesicle F-box Domain Binding Kinase Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway SH3 Domain Binding Cellular Response To Hydrogen Sulfide Negative Regulation Of Spontaneous Neurotransmitter Secretion Histone Deacetylase Binding Response To Curcumin Negative Regulation Of Phosphorylation Uterine Epithelium Development Response To 1-oleoyl-sn-glycerol 3-phosphate Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of JNK Cascade Positive Regulation Of Mitochondrial Fusion Cellular Response To L-glutamine Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Response To Corticosteroid Negative Regulation Of Protein Autophosphorylation Oviduct Epithelium Development Regulation Of MAPK Cascade Negative Regulation Of Catalytic Activity Release From Viral Latency Type 2 Mitophagy Negative Regulation Of Mitochondrial Fission Regulation Of Endosome Organization Regulation Of Synaptic Vesicle Transport Sperm Mitochondrial Sheath Assembly Lewy Body Regulation Of Spontaneous Synaptic Transmission Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake
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