PLEKHO1 and FLNB

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		PLEKHO1	FLNB
Gene Name		pleckstrin homology domain containing, family O member 1	filamin B, beta
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Stress Fiber Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Cortex Actin Cytoskeleton Integral Component Of Membrane Z Disc Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Actin Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process		Cytoskeletal Anchoring At Plasma Membrane Signal Transduction Skeletal Muscle Tissue Development Cytokine-mediated Signaling Pathway Actin Cytoskeleton Organization Cell Differentiation
Pathways			ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		13 interactors: AKT1 AKT2 C10orf88 CSNK2A1 DNAJB1 FLNB IFI35 PSMC5 RPS20 SMAD5 SMURF1 TRAF6 USP7	17 interactors: ASB2 ATF7IP FBLIM1 FLNA GP1BA ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 RAD21 SMURF2 TRIM55 TSHR
Entrez ID		51177	2317
HPRD ID		12217	04543
Ensembl ID		ENSG00000023902	ENSG00000136068
Uniprot IDs		Q53GL0	E7EN95 O75369
PDB IDs		3AA1	2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Stimulus Cellular Response To Organic Substance Peripheral Nervous System Myelin Maintenance Protein Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Cell Surface Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Fatty Acid Beta-oxidation Enzyme Linked Receptor Protein Signaling Pathway Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Lipid Transport Response To Stimulus Apoptotic Process Glycogen Biosynthetic Process Regulation Of Cell Cycle Process Protein Polyubiquitination Programmed Cell Death Tissue Development Cell Death Death Regulation Of Proteasomal Protein Catabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Transport Positive Regulation Of Glucose Metabolic Process Signal Transduction Cellular Response To Growth Factor Stimulus Protein Ubiquitination Cellular Response To Cytokine Stimulus Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Positive Regulation Of Protein Catabolic Process Cellular Polysaccharide Biosynthetic Process Response To Growth Factor Regulation Of Glycogen Metabolic Process Schwann Cell Development Protein Modification By Small Protein Conjugation Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Glucose Transport Polysaccharide Biosynthetic Process Positive Regulation Of Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Signaling	Cell Activation Cell Adhesion Single Organismal Cell-cell Adhesion Signal Transduction Cellular Response To Stimulus Signaling Cell Communication Viral Entry Into Host Cell Entry Into Host Cell Lymphocyte Activation Cell Junction Assembly Regulation Of Peptidyl-tyrosine Phosphorylation Single-organism Behavior Cell Development Leukocyte Activation Amyloid Precursor Protein Catabolic Process Regulation Of Cellular Process Response To Stimulus Neuron Development Cell Fate Specification Behavior Interaction With Host Embryonic Morphogenesis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Cell Surface Receptor Signaling Pathway Homotypic Cell-cell Adhesion Leukocyte Differentiation Neuron Differentiation Integrin-mediated Signaling Pathway Tissue Development Cell Projection Organization Immune System Development Membrane Protein Ectodomain Proteolysis Notch Receptor Processing Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Signal Transduction Cell Differentiation Heterotypic Cell-cell Adhesion Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Stress Developmental Process Leukocyte Activation Involved In Immune Response B Cell Activation Blood Coagulation Cell-matrix Adhesion Hemostasis Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?			actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways
Tagcloud (Difference) ?			actionable algorithms asf1 assuming candidates distinguishing driver genomes grm1 hcf1 hierarchically interpreting involve machinery modules neutral organized passenger pou2f1 precisely presents prkcz psnv psnvs snvs thousands uncovered unexpectedly ways
Tagcloud (Intersection) ?