PLEKHO1 and IFI35

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		PLEKHO1	IFI35
Gene Name		pleckstrin homology domain containing, family O member 1	interferon-induced protein 35
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Cytokine-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AKT1 AKT2 C10orf88 CSNK2A1 DNAJB1 FLNB IFI35 PSMC5 RPS20 SMAD5 SMURF1 TRAF6 USP7	6 interactors: BATF CLEC4G KDM1A MAPK1 NMI PLEKHO1
Entrez ID		51177	3430
HPRD ID		12217	02844
Ensembl ID		ENSG00000023902	ENSG00000068079
Uniprot IDs		Q53GL0	P80217
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Stimulus Cellular Response To Organic Substance Peripheral Nervous System Myelin Maintenance Protein Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Cell Surface Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Fatty Acid Beta-oxidation Enzyme Linked Receptor Protein Signaling Pathway Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Lipid Transport Response To Stimulus Apoptotic Process Glycogen Biosynthetic Process Regulation Of Cell Cycle Process Protein Polyubiquitination Programmed Cell Death Tissue Development Cell Death Death Regulation Of Proteasomal Protein Catabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Transport Positive Regulation Of Glucose Metabolic Process Signal Transduction Cellular Response To Growth Factor Stimulus Protein Ubiquitination Cellular Response To Cytokine Stimulus Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Positive Regulation Of Protein Catabolic Process Cellular Polysaccharide Biosynthetic Process Response To Growth Factor Regulation Of Glycogen Metabolic Process Schwann Cell Development Protein Modification By Small Protein Conjugation Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Glucose Transport Polysaccharide Biosynthetic Process Positive Regulation Of Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Signaling	JAK-STAT Cascade Transcription, DNA-templated RNA Biosynthetic Process Myeloid Leukocyte Differentiation Regulation Of Primitive Erythrocyte Differentiation MAPK Import Into Nucleus RNA Metabolic Process Response To Stress Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Golgi Inheritance T-helper 2 Cell Differentiation Myeloid Cell Differentiation Defense Response Caveolin-mediated Endocytosis T-helper 17 Cell Lineage Commitment Cytosine Metabolic Process T-helper 17 Cell Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Leukocyte Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Regulation Of Golgi Organization Histone H3-K4 Demethylation Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Megakaryocyte Differentiation Type 2 Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Blood Coagulation Intracellular Signal Transduction Hemostasis Positive Regulation Of Hormone Biosynthetic Process Lymphoid Progenitor Cell Differentiation Regulation Of Early Endosome To Late Endosome Transport Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Hematopoietic Stem Cell Differentiation T-helper Cell Lineage Commitment Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Gland Development
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