PLEKHO1 and DNAJB1

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		PLEKHO1	DNAJB1
Gene Name		pleckstrin homology domain containing, family O member 1	DnaJ (Hsp40) homolog, subfamily B, member 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	ATPase Activator Activity Protein Binding Hsp70 Protein Binding Unfolded Protein Binding Chaperone Binding ATPase Binding
	Biological Process		Response To Unfolded Protein Positive Regulation Of ATPase Activity Cellular Response To Heat Chaperone Mediated Protein Folding Requiring Cofactor Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways			HSF1-dependent transactivation Attenuation phase Cellular response to heat stress Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AKT1 AKT2 C10orf88 CSNK2A1 DNAJB1 FLNB IFI35 PSMC5 RPS20 SMAD5 SMURF1 TRAF6 USP7	28 interactors: A2M AKT1 ANK2 APP BRCA1 BRMS1 CENPE CYP2C8 DNAJC3 ECSIT FANCA FANCC GLB1 HSF1 HSPA1A HSPA4 HSPA8 MAST1 NQO1 NRAS PLEKHO1 PSEN2 PTGES3 SOD1 SPP1 STUB1 TERF1 ZFP36
Entrez ID		51177	3337
HPRD ID		12217	05198
Ensembl ID		ENSG00000023902	ENSG00000132002
Uniprot IDs		Q53GL0	B4DX52 P25685 Q6FHS4
PDB IDs		3AA1	1HDJ 2QLD 3AGX 3AGY 3AGZ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Stimulus Cellular Response To Organic Substance Peripheral Nervous System Myelin Maintenance Protein Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Cell Surface Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Fatty Acid Beta-oxidation Enzyme Linked Receptor Protein Signaling Pathway Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Lipid Transport Response To Stimulus Apoptotic Process Glycogen Biosynthetic Process Regulation Of Cell Cycle Process Protein Polyubiquitination Programmed Cell Death Tissue Development Cell Death Death Regulation Of Proteasomal Protein Catabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Transport Positive Regulation Of Glucose Metabolic Process Signal Transduction Cellular Response To Growth Factor Stimulus Protein Ubiquitination Cellular Response To Cytokine Stimulus Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Positive Regulation Of Protein Catabolic Process Cellular Polysaccharide Biosynthetic Process Response To Growth Factor Regulation Of Glycogen Metabolic Process Schwann Cell Development Protein Modification By Small Protein Conjugation Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process Positive Regulation Of Glucose Transport Polysaccharide Biosynthetic Process Positive Regulation Of Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Signaling	Response To Stress Response To Stimulus Response To External Stimulus Response To Heat Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Temperature Stimulus Response To Organic Substance Negative Regulation Of Cellular Protein Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Protein Metabolic Process Response To Unfolded Protein Cellular Response To Heat Negative Regulation Of Cellular Metabolic Process Removal Of Superoxide Radicals Cellular Response To Superoxide Protein Refolding Developmental Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Cell Morphogenesis Involved In Neuron Differentiation Response To Superoxide Response To Oxygen Radical Chemotaxis Regulation Of Cell Death Regulation Of Catalytic Activity Axon Guidance Positive Regulation Of Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Metabolic Process Response To Oxidative Stress Blood Coagulation Hemostasis Reactive Oxygen Species Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Differentiation Superoxide Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Kinase Activity Movement Of Cell Or Subcellular Component Axonogenesis Regulation Of Cellular Component Organization
Tagcloud ?			chaperone complement defective enlarged experimentally heat hsp hspa1a hspa6 hsps initiated interpreted keratinocytes knockin nfkappab nodes participation peroxisome physiologic ppar proliferator represses repression shock spleen stressed tnfalpha tnip1
Tagcloud (Difference) ?			chaperone complement defective enlarged experimentally heat hsp hspa1a hspa6 hsps initiated interpreted keratinocytes knockin nfkappab nodes participation peroxisome physiologic ppar proliferator represses repression shock spleen stressed tnfalpha tnip1
Tagcloud (Intersection) ?