LEF1 and SMAD1

  • Number of citations of the paper that reports this interaction (PMID 10890911)
  • 92
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

LEF1

SMAD1

Gene Name lymphoid enhancer-binding factor 1 SMAD family member 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 28 interactors: ALX4 ALYREF CDX1 CTNNB1 DPYSL2 EP300 KPNA1 KPNA2 MITF NARF NLK NOTCH1 PIAS4 PITX2 RNF138 RUNX2 SETD8 SMAD1 SMAD2 SMAD3 SMAD4 STAT5A SUMO2 TLE1 TLE2 TRA UBTF ZBTB3 138 interactors: ACVR1 ACVRL1 AKR1B1 ANKRD27 AP2A2 APP AR ARHGEF6 ARL4D BMPR1A BTBD2 BTG2 CAMSAP1 CDK7 CDK9 CHMP3 COL4A1 DVL1 ECSIT EIF2AK4 ELP3 EP300 ERBB2IP EWSR1 FBXL12 FBXO30 FHL5 FOXG1 FRZB GDF6 GLI3 GMEB1 GSC GSK3B HBP1 HIPK2 HOXA13 HOXA5 HOXC8 HOXD13 ICK ING2 INPP4A IRF2BP1 KAT2B KMT2D LEF1 LEMD3 MAPK1 MAST4 MBD1 MECOM MED6 MEN1 MGA MKL2 NAT9 NEDD4 NEDD9 NEUROG1 NKX3-2 NOTCH2 OAZ1 OAZ3 PAK1 PARD3B PIAS1 PIAS4 PIGQ PLEKHB1 PREB PSMB4 PSMD1 PSMD11 PUM1 RAB2B RAB30 RAB34 RAB38 RAB3B RAB6B RAC2 RAN RAP2A RASD2 RASL12 RFX1 RHEBL1 RHOG RPS27A SF3B1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMARCE1 SMURF1 SMURF2 SNIP1 SNRNP70 SOX5 SQSTM1 SS18L1 STARD13 STUB1 SUV39H1 TCF20 TGFBR1 TNNT1 TOB1 TRIP6 TTF1 TTF2 UBA52 UBC UBE2Z UBXN1 USP45 VEPH1 WDR77 XPC XPO1 YAP1 YY1 ZBTB44 ZDHHC3 ZEB2 ZNF251 ZNF423 ZNF510 ZNF512B ZNF521 ZNF76 ZNF8 ZSCAN4
Entrez ID 51176 4086
HPRD ID 01075 03356
Ensembl ID ENSG00000138795 ENSG00000170365
Uniprot IDs Q659G9 Q9UJU2 Q15797
PDB IDs 1KHU 2LAW 2LAX 2LAY 2LAZ 2LB0 2LB1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
Tagcloud (Difference) ?
abolishes  accumulations  allowing  bulge  collectively  constitutes  disrupted  drives  follicle  gatekeeper  give  hair  heterogeneity  initiating  interferes  intriguingly  mechanistically  mimics  normally  plasticity  propagation  protecting  rise  sc  scs  sebaceous  tumour  tumours  uncontrolled 
balance  cav1  collagens  cytokeratin  dialytic  discontinuation  emt  eventually  fibrosis  fluids  fn  fsp  hyperactivation  invading  junction  laminin  matrices  mcs  mek  mesothelial  pd  peritoneal  peritoneum  proteomics  smad2  snail  stroma  thickness  zo 
Tagcloud (Intersection) ?