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ODF2L and ERBB3
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ODF2L
ERBB3
Gene Name
outer dense fiber of sperm tails 2-like
erb-b2 receptor tyrosine kinase 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Centrosome
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Receptor Complex
Molecular Function
Protein Tyrosine Kinase Activity
Transmembrane Signaling Receptor Activity
Protein Binding
ATP Binding
Growth Factor Binding
Protein Tyrosine Kinase Activator Activity
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Biological Process
Endocardial Cushion Development
Protein Phosphorylation
Negative Regulation Of Cell Adhesion
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Peripheral Nervous System Development
Heart Development
Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Schwann Cell Differentiation
Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Cranial Nerve Development
Fc-epsilon Receptor Signaling Pathway
Wound Healing
Regulation Of Cell Proliferation
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Negative Regulation Of Secretion
Neuron Apoptotic Process
Positive Regulation Of Protein Tyrosine Kinase Activity
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Type 1 diabetes (
19430480
18198356
17554260
17554300
18978792
)
Type 1 diabetes autoantibodies (
21829393
)
Vitiligo (
22951725
)
Protein-Protein Interactions
5 interactors:
APP
ERBB3
KIAA1377
PIPOX
PRSS23
66 interactors:
ABL1
ABL2
AGTR2
BCAR3
CD82
CDK5
CHN2
CRK
CRKL
DAB1
DAPP1
EGF
EGFR
EGR1
ERBB2
ERBB4
FER
FGFR1
FLNA
FLYWCH1
GRB2
GRB7
HCK
HDAC6
IL6ST
ITK
JAK2
JAK3
MUC1
NCK1
NCK2
NEDD4
NRG1
NRG2
ODF2L
PA2G4
PIK3R1
PIK3R2
PIK3R3
PLCG1
PTGES3
PTK2
PTK2B
PTK6
RASA1
RASA4
RGS4
RIN1
RNF41
RPN1
SH2B3
SH2D1A
SHC1
SHC3
SOS1
SRC
SYK
TNS2
TNS3
TNS4
TXK
VAV1
VAV2
VAV3
ZAP70
ZNF207
Entrez ID
57489
2065
HPRD ID
11134
01820
Ensembl ID
ENSG00000122417
ENSG00000065361
Uniprot IDs
Q9ULJ1
P21860
PDB IDs
1M6B
2L9U
3KEX
3LMG
3P11
4LEO
Enriched GO Terms of Interacting Partners
?
Neuron Apoptotic Process
Regulation Of Protein Tyrosine Kinase Activity
Neuron Death
L-lysine Catabolic Process To Acetyl-CoA Via L-pipecolate
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Regulation Of Peptidyl-tyrosine Phosphorylation
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Lysine Catabolic Process
Neuron Remodeling
Regulation Of Cellular Amino Acid Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Fc Receptor Signaling Pathway
ERBB Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Innate Immune Response
Cell Communication
Immune Response-regulating Signaling Pathway
Regulation Of Signal Transduction
Signaling
Regulation Of Signaling
Cell Migration
Signal Transduction
Immune Response
Regulation Of Immune Response
Peptidyl-tyrosine Autophosphorylation
Cell Motility
Locomotion
Positive Regulation Of Signal Transduction
Regulation Of Immune System Process
Intracellular Signal Transduction
Defense Response
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Phosphorylation
Immune System Process
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Regulation Of Intracellular Signal Transduction
Protein Autophosphorylation
Peptidyl-tyrosine Phosphorylation
Cellular Response To Stimulus
Regulation Of Kinase Activity
Regulation Of Catalytic Activity
Fc-epsilon Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Metabolic Process
Cellular Response To Organic Substance
Cell Activation
Response To Growth Factor
Response To Stress
Positive Regulation Of Catalytic Activity
Response To Stimulus
Wound Healing
Response To Organic Substance
Cellular Response To Growth Factor Stimulus
Regulation Of Cell Proliferation
Blood Coagulation
Hemostasis
Tagcloud
?
acquire
alteration
associate
cascades
concurrent
dependence
egf
enhancing
latent
mapk
mediators
p42
p44
phosphotyrosine
potentiates
potentiating
predicts
prime
priming
progestin
progestins
r5020
shc
shift
stat5
steroid
switches
synergistically
waf1
Tagcloud (Difference)
?
acquire
alteration
associate
cascades
concurrent
dependence
egf
enhancing
latent
mapk
mediators
p42
p44
phosphotyrosine
potentiates
potentiating
predicts
prime
priming
progestin
progestins
r5020
shc
shift
stat5
steroid
switches
synergistically
waf1
Tagcloud (Intersection)
?