PCNA and FEN1

  • Number of citations of the paper that reports this interaction (PMID 7673186)
  • 78
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, two hybrid, in vitro)

PCNA

FEN1

Gene Name proliferating cell nuclear antigen flap structure-specific endonuclease 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolite levels ( 23378610)
  • Oleic acid (18:1n-9) plasma levels ( 23362303)
  • Palmitoleic acid (16:1n-7) plasma levels ( 23362303)
  • Phospholipid levels (plasma) ( 21829377)
  • Platelet counts ( 22139419)
  • Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions 116 interactors: ALDOA APEX1 APEX2 ATAD5 BAZ1B CBX1 CCNB1 CCND1 CCND3 CCNO CDC25C CDC6 CDK1 CDK2 CDK5 CDK6 CDKN1A CDKN1C CDKN2A CDT1 CHAF1A CHTF18 CHTF8 DHX9 DNMT1 DNTT DNTTIP2 DSCC1 DTL EGFR ENO1 EP300 ERCC5 EXO1 FANCD2 FANCL FEN1 GADD45A GADD45B GADD45G GAPDH GCK GPI HDAC1 HLTF HUS1 ING1 KCTD13 LDHA LIG1 MCL1 MLH1 MSH2 MSH3 MSH6 MUTYH MYBBP1A PARP1 PARP10 PFKM PGAM1 PGK1 PKLR PMS2 POLB POLD1 POLD2 POLD3 POLD4 POLDIP2 POLE POLH POLI POLL POLM PPP1CA PRKDC PTMA RAD18 RAD9A RBBP8 RFC1 RFC2 RFC3 RFC4 RFC5 RNF8 RPA1 SEC23IP SETD8 SHPRH SIVA1 SMARCAD1 SPRTN SUB1 TCOF1 TDG TIRAP TMEM218 TPI1 UBB UBE2A UBE2B UBE2D3 UHRF2 UNG USP1 USP2 USP4 WDR48 WRN XRCC1 XRCC5 XRCC6 YBX1 ZBTB1 15 interactors: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 PCNA RAD1 TERF1 WRN
Entrez ID 5111 2237
HPRD ID 01456 02670
Ensembl ID ENSG00000132646 ENSG00000168496
Uniprot IDs P12004 P39748 Q6FHX6
PDB IDs 1AXC 1U76 1U7B 1UL1 1VYJ 1VYM 1W60 2ZVK 2ZVL 2ZVM 3P87 3TBL 3VKX 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
alka  alphaherpesvirus  analogy  backbone  cnjb  complexed  contrasts  crystallographic  emb  endonuclease  helical  helix  hhh  kinesin  kraut  kumar  motifs  nitrogens  nuclease  pelletier  pol  primer  sawaya  searches  shutoff  spt6  taq  virion  wilson 
Tagcloud (Intersection) ?