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FIS1 and MARCH5
Number of citations of the paper that reports this interaction (PMID
16874301
)
79
Data Source:
HPRD
(in vivo)
FIS1
MARCH5
Gene Name
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
membrane-associated ring finger (C3HC4) 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein Complex
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Receptor Binding
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
GTPase Binding
Biological Process
Mitochondrial Fission
Mitochondrion Degradation
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Protein Homooligomerization
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Protein Polyubiquitination
Protein Autoubiquitination
Protein Localization To Mitochondrion
Regulation Of Mitochondrial Fission
Positive Regulation Of Mitochondrial Fission
Negative Regulation Of Cell Aging
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
A2M
BCAP31
CCDC155
DNM1L
MARCH5
NOS3
PEX5
TBC1D15
UBC
VKORC1
17 interactors:
AKTIP
FATE1
FIS1
MAP1B
MFN2
SOD1
TANK
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2I
UBE2N
UBE2T
UBE2W
UTRN
Entrez ID
51024
54708
HPRD ID
12352
07909
Ensembl ID
ENSG00000214253
ENSG00000198060
Uniprot IDs
Q9Y3D6
B4DGV8
Q9NX47
PDB IDs
1NZN
1PC2
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Mitochondrial Fission
Cellular Localization
Regulation Of Mitochondrial Fission
Protein Localization To Organelle
Regulation Of Protein Oligomerization
Peroxisome Organization
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Protein Localization To Mitochondrion
Execution Phase Of Apoptosis
Chromosome Localization To Nuclear Envelope Involved In Synapsis
Mitochondrial Membrane Fission
Dynamin Polymerization Involved In Mitochondrial Fission
Oogenesis
Mitochondrion Organization
Blood Coagulation
Regulation Of Signaling
Hemostasis
Regulation Of Mitochondrion Organization
Establishment Of Localization In Cell
Negative Regulation Of Protein Homotetramerization
Smooth Muscle Hyperplasia
Negative Regulation Of Complement Activation, Lectin Pathway
Protein Tetramerization
Female Gamete Generation
Spermatogenesis
Male Gamete Generation
Regulation Of Peroxisome Organization
Protein Import Into Peroxisome Matrix, Translocation
Regulation Of Body Fluid Levels
Second-messenger-mediated Signaling
Positive Regulation Of Apoptotic Process
Regulation Of Catalytic Activity
Positive Regulation Of Programmed Cell Death
Cellular Protein Localization
Smooth Muscle Adaptation
Protein Import Into Peroxisome Matrix, Docking
Wound Healing
Positive Regulation Of Cell Death
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Regulation Of Intrinsic Apoptotic Signaling Pathway
Gamete Generation
Negative Regulation Of Muscle Hyperplasia
Regulation Of Systemic Arterial Blood Pressure By Endothelin
Regulation Of Apoptotic Process
Protein Polyubiquitination
Regulation Of Proteolysis
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein K11-linked Ubiquitination
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Protein Monoubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Innate Immune Response
Regulation Of Innate Immune Response
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Cellular Protein Modification Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Transferase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stress
Proteolysis
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Immune Response
Cellular Response To Oxygen Levels
Positive Regulation Of Cellular Protein Metabolic Process
Mitochondrial Fusion
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Ubiquitination
Cellular Protein Metabolic Process
Response To Stress
Regulation Of Immune System Process
Innate Immune Response
Regulation Of Immune Response
Tagcloud
?
app
atrophy
biogenesis
cognitive
compensate
defect
deficits
drp1
dynamin
feature
fission
injected
mfn1
mfn2
mitochondria
mitochondrial
mitofusion
nsc
nscs
opa1
optic
prominent
ps1
rescue
susceptible
tg
transplantation
veh
vehicle
Tagcloud (Difference)
?
app
atrophy
biogenesis
cognitive
compensate
defect
deficits
drp1
dynamin
feature
fission
injected
mfn1
mfn2
mitochondria
mitochondrial
mitofusion
nsc
nscs
opa1
optic
prominent
ps1
rescue
susceptible
tg
transplantation
veh
vehicle
Tagcloud (Intersection)
?