FIS1 and SLC14A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FIS1	SLC14A1
Description		fission, mitochondrial 1	solute carrier family 14 member 1 (Kidd blood group)
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Cytosol Membrane Protein-containing Complex	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Molecular Adaptor Activity	Water Transmembrane Transporter Activity Protein Binding Urea Transmembrane Transporter Activity Urea Channel Activity
	Biological Process	Mitochondrial Fission Protein Targeting To Mitochondrion Apoptotic Process Mitochondrion Organization Response To Muscle Activity Peroxisome Fission Response To Nutrient Levels Response To Endoplasmic Reticulum Stress Positive Regulation Of Neuron Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Cellular Response To Glucose Stimulus Cellular Response To Lipid Positive Regulation Of Mitochondrial Fission Cellular Response To Toxic Substance Cellular Response To Peptide Response To Fluoride Negative Regulation Of ATP Metabolic Process Response To Flavonoid Response To Hypobaric Hypoxia Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Water Transport Urea Transport Establishment Of Localization In Cell Transmembrane Transport Urea Transmembrane Transport
Pathways		Class I peroxisomal membrane protein import	SLC-mediated transport of organic cations
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)	Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)
Interacting Genes		31 interacting genes: A2M ABHD6 APH1A AQP6 BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1	12 interacting genes: BTN2A2 C1GALT1 CFTR FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE
Entrez ID		51024	6563
HPRD ID		12352	00195
Ensembl ID		ENSG00000214253	ENSG00000141469
Uniprot IDs		Q9Y3D6	B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336
PDB IDs		1NZN 1PC2 7YA9 7YKA 8U1Z 8XWX	6QD5 8BLP 8XDF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Monoatomic Ion Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Monoatomic Cation Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Endoplasmic Reticulum Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Golgi Membrane Transmembrane Transport Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Mitochondrial Outer Membrane Dopamine Transport Neurotransmitter Reuptake Metal Ion Transport Positive Regulation Of Mitochondrial Fission Neutrophil Mediated Immunity Xenobiotic Transmembrane Transporter Activity Water Transport One-carbon Compound Transport Cellular Detoxification Positive Regulation Of Protein Transport	Membrane Water Transport
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