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FIS1
Gene Name
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Peroxisome
Integral Component Of Peroxisomal Membrane
Membrane
Integral Component Of Mitochondrial Outer Membrane
Protein Complex
Molecular Function
Receptor Binding
Protein Binding
Biological Process
Mitochondrial Fission
Mitochondrion Degradation
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Positive Regulation Of Cytosolic Calcium Ion Concentration
Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Peroxisome Fission
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Protein Homooligomerization
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Mitochondrion Morphogenesis
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Protein Targeting To Membrane
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
A2M
BCAP31
CCDC155
DNM1L
MARCH5
NOS3
PEX5
TBC1D15
UBC
VKORC1
Entrez ID
51024
HPRD ID
12352
Ensembl ID
ENSG00000214253
Uniprot IDs
Q9Y3D6
PDB IDs
1NZN
1PC2
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Mitochondrial Fission
Cellular Localization
Regulation Of Mitochondrial Fission
Protein Localization To Organelle
Regulation Of Protein Oligomerization
Peroxisome Organization
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Protein Localization To Mitochondrion
Execution Phase Of Apoptosis
Chromosome Localization To Nuclear Envelope Involved In Synapsis
Mitochondrial Membrane Fission
Dynamin Polymerization Involved In Mitochondrial Fission
Oogenesis
Mitochondrion Organization
Blood Coagulation
Regulation Of Signaling
Hemostasis
Regulation Of Mitochondrion Organization
Establishment Of Localization In Cell
Negative Regulation Of Protein Homotetramerization
Smooth Muscle Hyperplasia
Negative Regulation Of Complement Activation, Lectin Pathway
Protein Tetramerization
Female Gamete Generation
Spermatogenesis
Male Gamete Generation
Regulation Of Peroxisome Organization
Protein Import Into Peroxisome Matrix, Translocation
Regulation Of Body Fluid Levels
Second-messenger-mediated Signaling
Positive Regulation Of Apoptotic Process
Regulation Of Catalytic Activity
Positive Regulation Of Programmed Cell Death
Cellular Protein Localization
Smooth Muscle Adaptation
Protein Import Into Peroxisome Matrix, Docking
Wound Healing
Positive Regulation Of Cell Death
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Regulation Of Intrinsic Apoptotic Signaling Pathway
Gamete Generation
Negative Regulation Of Muscle Hyperplasia
Regulation Of Systemic Arterial Blood Pressure By Endothelin
Regulation Of Apoptotic Process
Protein Polyubiquitination
Regulation Of Proteolysis
Tagcloud
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app
atrophy
biogenesis
cognitive
compensate
defect
deficits
drp1
dynamin
feature
fission
injected
mfn1
mfn2
mitochondria
mitochondrial
mitofusion
nsc
nscs
opa1
optic
prominent
ps1
rescue
susceptible
tg
transplantation
veh
vehicle