FIS1 and BCAP31

Number of citations of the paper that reports this interaction (PMID 21183955)
21

Data Source:
BioGRID (pull down, pull down)

		FIS1	BCAP31
Gene Name		fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	B-cell receptor-associated protein 31
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Peroxisome Integral Component Of Peroxisomal Membrane Membrane Integral Component Of Mitochondrial Outer Membrane Protein Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Particle Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Receptor Binding Protein Binding	Protein Binding Protein Complex Binding MHC Class I Protein Binding
	Biological Process	Mitochondrial Fission Mitochondrion Degradation Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Protein Homooligomerization Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase Class I MHC mediated antigen processing & presentation Antigen Presentation: Folding, assembly and peptide loading of class I MHC Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: A2M BCAP31 CCDC155 DNM1L MARCH5 NOS3 PEX5 TBC1D15 UBC VKORC1	25 interactors: ACTG1 APP BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		51024	10134
HPRD ID		12352	02319
Ensembl ID		ENSG00000214253	ENSG00000185825
Uniprot IDs		Q9Y3D6	P51572
PDB IDs		1NZN 1PC2	4JZL 4JZP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Cellular Localization Regulation Of Mitochondrial Fission Protein Localization To Organelle Regulation Of Protein Oligomerization Peroxisome Organization Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Protein Localization To Mitochondrion Execution Phase Of Apoptosis Chromosome Localization To Nuclear Envelope Involved In Synapsis Mitochondrial Membrane Fission Dynamin Polymerization Involved In Mitochondrial Fission Oogenesis Mitochondrion Organization Blood Coagulation Regulation Of Signaling Hemostasis Regulation Of Mitochondrion Organization Establishment Of Localization In Cell Negative Regulation Of Protein Homotetramerization Smooth Muscle Hyperplasia Negative Regulation Of Complement Activation, Lectin Pathway Protein Tetramerization Female Gamete Generation Spermatogenesis Male Gamete Generation Regulation Of Peroxisome Organization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Body Fluid Levels Second-messenger-mediated Signaling Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Cellular Protein Localization Smooth Muscle Adaptation Protein Import Into Peroxisome Matrix, Docking Wound Healing Positive Regulation Of Cell Death Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Intrinsic Apoptotic Signaling Pathway Gamete Generation Negative Regulation Of Muscle Hyperplasia Regulation Of Systemic Arterial Blood Pressure By Endothelin Regulation Of Apoptotic Process Protein Polyubiquitination Regulation Of Proteolysis	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Establishment Of Localization In Cell Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrion Organization Vesicle-mediated Transport Membrane Organization Cellular Localization Apoptotic Process Response To Wounding Neuron Apoptotic Process Immune System Process Programmed Cell Death Positive Regulation Of Peptidase Activity Positive Regulation Of Mitochondrion Organization Cell Death Death Neuron Death Secretion By Cell Apoptotic Mitochondrial Changes Exocytosis Apoptotic Signaling Pathway Organelle Fusion Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Transport Positive Regulation Of Cell Death Regulation Of Endopeptidase Activity Secretion Immune Response Positive Regulation Of Organelle Organization Regulation Of Peptidase Activity Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Membrane Fusion Intracellular Transport Regulation Of Protein Localization Positive Regulation Of Endopeptidase Activity
Tagcloud ?		app atrophy biogenesis cognitive compensate defect deficits drp1 dynamin feature fission injected mfn1 mfn2 mitochondria mitochondrial mitofusion nsc nscs opa1 optic prominent ps1 rescue susceptible tg transplantation veh vehicle	24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Difference) ?		app atrophy biogenesis cognitive compensate defect deficits drp1 dynamin feature fission injected mfn1 mfn2 mitochondria mitochondrial mitofusion nsc nscs opa1 optic prominent ps1 rescue susceptible tg transplantation veh vehicle	24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Intersection) ?