WASHC3 and SNAPIN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		WASHC3	SNAPIN
Description		WASH complex subunit 3	SNAP associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Early Endosome Membrane WASH Complex	Golgi Membrane Acrosomal Vesicle Manchette Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Cytosol Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Synapse Perinuclear Region Of Cytoplasm Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm Microvesicle
	Molecular Function	Protein Binding	SNARE Binding Protein Binding
	Biological Process	Exocytosis Protein Transport Endosomal Transport Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Intracellular Protein Transport Exocytosis Lysosome Organization Lysosomal Lumen Acidification Chemical Synaptic Transmission Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Protein-containing Complex Localization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Protein Maturation Establishment Of Vesicle Localization Regulation Of Lysosome Size Neuron Cellular Homeostasis Organelle Transport Along Microtubule Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		55 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1	103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYRK3 DYSF EBAG9 EEF1G ELP1 ENO3 EXOC7 FAM114A1 FSD2 GPRASP1 GRIK1 HAP1 HMGB2 IKBIP IMMT KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MORC3 MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ
Entrez ID		51019	23557
HPRD ID		13031	06111
Ensembl ID		ENSG00000120860	ENSG00000143553
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	O95295
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization BLOC-1 Complex Cytoskeleton Organization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Cytoskeleton Axonal Transport Transport Along Microtubule Microtubule-based Process Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Anterograde Axonal Transport Microtubule-based Transport Syntaxin Binding Cellular Localization Supramolecular Fiber Organization Establishment Of Localization In Cell Intermediate Filament Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Establishment Of Protein Localization Organelle Transport Along Microtubule Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Vesicle Transport Along Microtubule Intracellular Transport Centrosome Cycle Establishment Of Vesicle Localization Intracellular Protein Localization Protein Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Structural Constituent Of Skin Epidermis Vesicle Localization Organelle Assembly Neuron Projection Development Spindle Pole Microtubule Organizing Center Organization Centriole Keratin Filament Mitotic Sister Chromatid Segregation Membraneless Organelle Assembly Localization Within Membrane Regulation Of Lysosome Size BORC Complex Sister Chromatid Segregation	Cytoskeleton Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Establishment Of Organelle Localization Intermediate Filament Supramolecular Fiber Organization Organelle Localization Structural Constituent Of Cytoskeleton BLOC-1 Complex Actin Filament Binding Synaptic Vesicle Transport Establishment Of Vesicle Localization Structural Molecule Activity Axo-dendritic Transport Axon Cytoplasm Axonal Transport Vesicle Localization Establishment Of Localization In Cell Anterograde Axonal Transport Cytosol Anterograde Synaptic Vesicle Transport Muscle Thin Filament Tropomyosin Structural Constituent Of Skin Epidermis Cytoplasm Transport Along Microtubule Vesicle Transport Along Microtubule Cellular Localization Cytoskeleton-dependent Intracellular Transport Vesicle Cytoskeletal Trafficking Regulation Of Cellular Component Organization Microtubule-based Transport Melanosome Organization Keratin Filament Intracellular Transport Pigment Granule Organization Structural Constituent Of Muscle Actomyosin Structure Organization Muscle System Process Actin Binding Muscle Contraction Extracellular Exosome Contractile Muscle Fiber Stress Fiber Organelle Transport Along Microtubule Tissue Morphogenesis Intracellular Protein Localization Z Disc
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