WASHC3 and CENPK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		WASHC3	CENPK
Description		WASH complex subunit 3	centromere protein K
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Early Endosome Membrane WASH Complex	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Exocytosis Protein Transport Endosomal Transport Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Mitotic Sister Chromatid Segregation Chromosome Segregation Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		55 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1	10 interacting genes: AP1G2 HSPB1 MRFAP1L1 PCBD2 PEX14 RTN4IP1 SOX6 TRIM55 TRIM63 WASHC3
Entrez ID		51019	64105
HPRD ID		13031	13323
Ensembl ID		ENSG00000120860	ENSG00000123219
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	D6RHD3 D6RJF0 Q9BS16
PDB IDs			7PB4 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Organelle Organization BLOC-1 Complex Cytoskeleton Organization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Cytoskeleton Axonal Transport Transport Along Microtubule Microtubule-based Process Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Anterograde Axonal Transport Microtubule-based Transport Syntaxin Binding Cellular Localization Supramolecular Fiber Organization Establishment Of Localization In Cell Intermediate Filament Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Establishment Of Protein Localization Organelle Transport Along Microtubule Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Vesicle Transport Along Microtubule Intracellular Transport Centrosome Cycle Establishment Of Vesicle Localization Intracellular Protein Localization Protein Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Structural Constituent Of Skin Epidermis Vesicle Localization Organelle Assembly Neuron Projection Development Spindle Pole Microtubule Organizing Center Organization Centriole Keratin Filament Mitotic Sister Chromatid Segregation Membraneless Organelle Assembly Localization Within Membrane Regulation Of Lysosome Size BORC Complex Sister Chromatid Segregation	Contractile Muscle Fiber
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