WASHC3 and KRT6A

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WASHC3	KRT6A
Description		WASH complex subunit 3	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Early Endosome Membrane WASH Complex	Nucleus Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Exocytosis Protein Transport Endosomal Transport Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Morphogenesis Of An Epithelium Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Killing Of Cells Of Another Organism Wound Healing Intermediate Filament Organization Defense Response To Gram-positive Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Appendicular lean mass ( 33097823)	Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		55 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1	37 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		51019	3853
HPRD ID		13031	01011
Ensembl ID		ENSG00000120860	ENSG00000205420
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?		Organelle Organization BLOC-1 Complex Cytoskeleton Organization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Cytoskeleton Axonal Transport Transport Along Microtubule Microtubule-based Process Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Anterograde Axonal Transport Microtubule-based Transport Syntaxin Binding Cellular Localization Supramolecular Fiber Organization Establishment Of Localization In Cell Intermediate Filament Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Establishment Of Protein Localization Organelle Transport Along Microtubule Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Vesicle Transport Along Microtubule Intracellular Transport Centrosome Cycle Establishment Of Vesicle Localization Intracellular Protein Localization Protein Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Structural Constituent Of Skin Epidermis Vesicle Localization Organelle Assembly Neuron Projection Development Spindle Pole Microtubule Organizing Center Organization Centriole Keratin Filament Mitotic Sister Chromatid Segregation Membraneless Organelle Assembly Localization Within Membrane Regulation Of Lysosome Size BORC Complex Sister Chromatid Segregation	Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Epithelial Cell Differentiation Cytoskeleton Organelle Organization Tissue Morphogenesis Morphogenesis Of An Epithelium Structural Constituent Of Cytoskeleton Keratinization Extracellular Exosome Cellular Developmental Process Intermediate Filament Cytoskeleton Cell Differentiation Anatomical Structure Morphogenesis Hair Follicle Morphogenesis Epidermis Development Developmental Process Scaffold Protein Binding Cytosol Hair Cycle Process Protein Binding Adherens Junction Cornified Envelope Tissue Development Epithelial Cell-cell Adhesion Peptide Cross-linking Positive Regulation Of ERAD Pathway
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