WASHC3 and IFT20

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		WASHC3	IFT20
Description		WASH complex subunit 3	intraflagellar transport 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Early Endosome Membrane WASH Complex	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body
	Molecular Function	Protein Binding	Opsin Binding Protein Binding Small GTPase Binding
	Biological Process	Exocytosis Protein Transport Endosomal Transport Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Osteoprotegerin levels ( 25080503)
Interacting Genes		55 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1	46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17
Entrez ID		51019	90410
HPRD ID		13031	17137
Ensembl ID		ENSG00000120860	ENSG00000109083
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	A0A087X2B4 Q8IY31
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization BLOC-1 Complex Cytoskeleton Organization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Cytoskeleton Axonal Transport Transport Along Microtubule Microtubule-based Process Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Anterograde Axonal Transport Microtubule-based Transport Syntaxin Binding Cellular Localization Supramolecular Fiber Organization Establishment Of Localization In Cell Intermediate Filament Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Establishment Of Protein Localization Organelle Transport Along Microtubule Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Vesicle Transport Along Microtubule Intracellular Transport Centrosome Cycle Establishment Of Vesicle Localization Intracellular Protein Localization Protein Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Structural Constituent Of Skin Epidermis Vesicle Localization Organelle Assembly Neuron Projection Development Spindle Pole Microtubule Organizing Center Organization Centriole Keratin Filament Mitotic Sister Chromatid Segregation Membraneless Organelle Assembly Localization Within Membrane Regulation Of Lysosome Size BORC Complex Sister Chromatid Segregation	Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection
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