COPS7A and GPS1

Number of citations of the paper that reports this interaction (PMID 11337588)
171

Data Source:
HPRD (in vitro)

		COPS7A	GPS1
Gene Name		COP9 signalosome subunit 7A	G protein pathway suppressor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm COP9 Signalosome	Nucleus Cytoplasm COP9 Signalosome
	Molecular Function		GTPase Inhibitor Activity Protein Binding
	Biological Process	Cullin Deneddylation	Inactivation Of MAPK Activity Cell Cycle JNK Cascade Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: COPS2 COPS3 COPS4 COPS5 COPS8 CSNK2A1 CSNK2B CUL1 CUL5 EIF3E GPS1 JUN NFE2L2 PMF1 PPBP PRKD1 PSMD4 PTGS2 RAF1 TOM1L1 TP53	20 interactors: COPS2 COPS3 COPS5 COPS6 COPS7A COPS8 CUL1 CUL2 CUL3 CUL5 DDB1 IP6K1 ITPK1 JUN RBX1 SENP8 SKP1 SKP2 TBC1D17 TP53
Entrez ID		50813	2873
HPRD ID		16736	15991
Ensembl ID		ENSG00000111652	ENSG00000169727
Uniprot IDs		Q567U8 Q9UBW8	C9JFE4 Q13098
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Protein Modification By Small Protein Removal Regulation Of Cell Proliferation Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Cycle Signal Transduction Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Positive Regulation Of Protein Modification Process Cellular Metabolic Process Signaling Cellular Response To Stimulus Regulation Of Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Cell Communication Apoptotic Process Programmed Cell Death Regulation Of Catalytic Activity Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Signaling Mitotic Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Signal Transduction Cellular Protein Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Cell Cycle Apoptotic Signaling Pathway Protein Catabolic Process Regulation Of Cellular Process Intracellular Signal Transduction Negative Regulation Of Cell Death Response To Stimulus Mitotic Cell Cycle Process See more	Protein Deneddylation Cullin Deneddylation Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Monoubiquitination Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process G1/S Transition Of Mitotic Cell Cycle Proteolysis Viral Process Cellular Macromolecule Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Arrest Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Catabolic Process Mitotic Cell Cycle Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Mitotic Cell Cycle Notch Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Circadian Rhythm Cell Cycle Process Negative Regulation Of Cell Proliferation Regulation Of Cell Proliferation Regulation Of DNA-templated Transcription In Response To Stress Response To Abiotic Stimulus Cell Communication Metabolic Process Negative Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Signal Transduction Histone H2A Monoubiquitination Cell Cycle Histone H2A Ubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Signaling See more
Tagcloud ?		abomasum actb b2m blat butterfat calculating coro1b cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification	abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps2 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Difference) ?		abomasum actb b2m blat butterfat calculating coro1b cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification	abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps2 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Intersection) ?