BEGAIN and CATSPER1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BEGAIN	CATSPER1
Gene Name		brain-enriched guanylate kinase-associated	cation channel, sperm associated 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Dendrite Neuronal Cell Body	Plasma Membrane Motile Cilium CatSper Complex
	Molecular Function	Protein Binding	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding
	Biological Process		Multicellular Organismal Development Spermatogenesis Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Cell Differentiation Sperm Motility Multicellular Organism Reproduction Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Calcium Ion Transport Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways			Sperm Motility And Taxes Fertilization
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		23 interactors: ABLIM1 APP BAHD1 CATSPER1 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A GFI1B HGS HID1 KIAA0408 QSOX1 RBL1 RIBC2 TRIM27 USP2 ZFP64 ZNF250 ZNF417 ZNF774	33 interactors: ADAMTSL4 AGR2 APOA2 BEGAIN CHIC2 CHRD EFEMP2 EMD KHDRBS2 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI MTUS2 NOTCH2NL PLSCR1 PLSCR3 RFX6 RGS20 RIMBP3 SCRG1 SPRY2 TRAF2 TRIP6
Entrez ID		57596	117144
HPRD ID		06459	09396
Ensembl ID		ENSG00000183092	ENSG00000175294
Uniprot IDs		Q9BUH8	Q8NEC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Regulation Of Metabolic Process Protein Localization To Synapse Regulation Of Gene Expression Cell Recognition Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Cortical Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Establishment Or Maintenance Of Apical/basal Cell Polarity Axon Guidance Cortical Cytoskeleton Organization Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Ion Transmembrane Transport Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Receptor Clustering Axonogenesis Response To Brefeldin A Locomotory Behavior Gene Expression Negative Regulation Of Cellular Metabolic Process Nucleotide Phosphorylation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Recognition Chemotaxis Regulation Of Membrane Potential Regulation Of Ion Transport Negative Regulation Of Transcription, DNA-templated Neuron Projection Morphogenesis Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Neuromuscular Process Controlling Balance Synapse Assembly Negative Regulation Of RNA Biosynthetic Process Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury Cell Morphogenesis Involved In Differentiation	Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Phospholipid Scrambling Regulation Of Protein Localization Phospholipid Transport Regulation Of Cellular Localization Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Transport Regulation Of Signaling Regulation Of Protein Localization To Nucleus Glandular Epithelial Cell Differentiation Regulation Of Nucleocytoplasmic Transport BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Pancreatic Epsilon Cell Differentiation Negative Regulation Of Cholesterol Transporter Activity Pancreatic D Cell Differentiation I-kappaB Kinase/NF-kappaB Signaling Regulation Of Intracellular Protein Transport Positive Regulation Of Catalytic Activity Regulation Of Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of JUN Kinase Activity Regulation Of Membrane Lipid Distribution Negative Regulation Of Protein Import Into Nucleus Mucus Secretion Regulation Of Cholesterol Transporter Activity Negative Regulation Of Cholesterol Import Acute Inflammatory Response Regulation Of MAP Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Epithelium Development Cholesterol Homeostasis Lipid Transport Sterol Homeostasis Regulation Of JUN Kinase Activity Negative Regulation Of Protein Localization To Nucleus Lipid Localization Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Lung Goblet Cell Differentiation Regulation Of Cholesterol Import Negative Regulation Of Intracellular Protein Transport Tissue Development Regulation Of Transcription Factor Import Into Nucleus Developmental Process Positive Regulation Of Nucleocytoplasmic Transport Lobar Bronchus Development Release Of Cytoplasmic Sequestered NF-kappaB Diacylglycerol Catabolic Process Lipid Homeostasis
Tagcloud ?			5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Difference) ?			5k3 alpl armitage beadchip bovinesnp50 bull capn1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Intersection) ?