BEGAIN and ABLIM1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BEGAIN	ABLIM1
Gene Name		brain-enriched guanylate kinase-associated	actin binding LIM protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Dendrite Neuronal Cell Body	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium
	Molecular Function	Protein Binding	Actin Binding Protein Binding Zinc Ion Binding
	Biological Process		Cytoskeleton Organization Axon Guidance Visual Perception Organ Morphogenesis Lamellipodium Assembly Cilium Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Axon guidance DCC mediated attractive signaling Netrin-1 signaling
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)	Obesity-related traits ( 23251661) Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		23 interactors: ABLIM1 APP BAHD1 CATSPER1 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A GFI1B HGS HID1 KIAA0408 QSOX1 RBL1 RIBC2 TRIM27 USP2 ZFP64 ZNF250 ZNF417 ZNF774	17 interactors: ACTB ACTG1 APP BEGAIN CALCOCO2 CARD9 GOLGA2 HOOK2 KCNJ12 KRT15 LDOC1 SREBF2 TRAF2 TSC22D4 USHBP1 VIM YWHAG
Entrez ID		57596	3983
HPRD ID		06459	03819
Ensembl ID		ENSG00000183092	ENSG00000099204
Uniprot IDs		Q9BUH8	B3KSG3 B3KVH2 B4DQA3 B7Z4H1 O14639
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Regulation Of Metabolic Process Protein Localization To Synapse Regulation Of Gene Expression Cell Recognition Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Cortical Actin Cytoskeleton Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Establishment Or Maintenance Of Apical/basal Cell Polarity Axon Guidance Cortical Cytoskeleton Organization Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Ion Transmembrane Transport Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Receptor Clustering Axonogenesis Response To Brefeldin A Locomotory Behavior Gene Expression Negative Regulation Of Cellular Metabolic Process Nucleotide Phosphorylation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Recognition Chemotaxis Regulation Of Membrane Potential Regulation Of Ion Transport Negative Regulation Of Transcription, DNA-templated Neuron Projection Morphogenesis Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Neuromuscular Process Controlling Balance Synapse Assembly Negative Regulation Of RNA Biosynthetic Process Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury Cell Morphogenesis Involved In Differentiation	Innate Immune Response Immune Response Regulation Of Protein Binding Defense Response Immune Response-regulating Signaling Pathway Platelet Activation Platelet Aggregation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Binding Positive Regulation Of Immune Response Retina Homeostasis Endocytosis Response To Stress Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Adherens Junction Organization Immune System Process Ephrin Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Axon Guidance Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Blood Coagulation Hemostasis Cholesterol Metabolic Process Generation Of Neurons Positive Regulation Of JNK Cascade Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cholesterol Efflux Sterol Metabolic Process Pattern Recognition Receptor Signaling Pathway Neurogenesis Innate Immune Response-activating Signal Transduction Positive Regulation Of Stress-activated MAPK Cascade Programmed Cell Death Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Activation Of Innate Immune Response Cell Death Death Positive Regulation Of Peptidase Activity Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Axonogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
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