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OPRK1 and GPRASP1
Number of citations of the paper that reports this interaction (PMID
15086532
)
18
Data Source:
BioGRID
(pull down)
OPRK1
GPRASP1
Gene Name
opioid receptor, kappa 1
G protein-coupled receptor associated sorting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Neuron Projection
Cytoplasm
Molecular Function
Opioid Receptor Activity
Protein Binding
Dynorphin Receptor Activity
Neuropeptide Binding
Protein Binding
Biological Process
Immune Response
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Neuropeptide Signaling Pathway
Synaptic Transmission
Sensory Perception
Behavior
Locomotory Behavior
Sensory Perception Of Pain
Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway
Opioid Receptor Signaling Pathway
Regulation Of Saliva Secretion
Defense Response To Virus
Endosome To Lysosome Transport
G-protein Coupled Receptor Catabolic Process
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Tramadol
Morphine
Codeine
Amitriptyline
Hydromorphone
Mirtazapine
Meperidine
Oxycodone
Butorphanol
Propoxyphene
Pentazocine
Naltrexone
Sufentanil
Fentanyl
Menthol
Loperamide
Nalbuphine
Levorphanol
Remifentanil
Buprenorphine
Naloxone
Dezocine
3-Methylthiofentanyl
Heroin
Etorphine
Carfentanil
Diprenorphine
Dihydromorphine
3-Methylfentanyl
Tapentadol
Alvimopan
Methylnaltrexone
Diseases
GWAS
Protein-Protein Interactions
5 interactors:
GABARAPL1
GNA15
GPRASP1
OPRD1
SLC9A3R1
47 interactors:
ADRB1
ADRB2
AGTR1
ATXN7
C8orf33
CALCR
CHRM1
CHRM2
CHRM3
CHRM4
CHRM5
CRIP1
CXCR2
F2R
F2RL1
GLP1R
GLYAT
GRM1
GRM5
GRM8
HGH1
HMOX2
HTR7
LAMTOR5
LRP2
MAP7D1
MLNR
MTF2
OFD1
OPRD1
OPRK1
OPRL1
OPRM1
OXTR
PBK
PER1
PFDN1
SNAPIN
STMN2
TAC3
TACR1
TACR2
TACR3
TBXA2R
TFG
TRAF4
VIPR1
Entrez ID
4986
9737
HPRD ID
01309
02333
Ensembl ID
ENSG00000082556
ENSG00000198932
Uniprot IDs
P41145
Q5JY77
PDB IDs
2A0D
2IQN
4DJH
Enriched GO Terms of Interacting Partners
?
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Dopamine Receptor Signaling Pathway
Renal Phosphate Ion Absorption
Glutathione Transport
G-protein Coupled Receptor Catabolic Process
Negative Regulation Of Sodium:proton Antiporter Activity
Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway
Renal Sodium Ion Transport
G-protein Coupled Receptor Signaling Pathway
Cellular Phosphate Ion Homeostasis
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Sodium:proton Antiporter Activity
Negative Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Protein Oligomerization
Bile Acid Secretion
Opioid Receptor Signaling Pathway
Oligopeptide Transport
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Renal Absorption
Regulation Of Proton Transport
Phosphate Ion Homeostasis
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Microvillus Assembly
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Microvillus Organization
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Cellular Ion Homeostasis
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of CREB Transcription Factor Activity
Receptor Catabolic Process
Nucleophagy
Cellular Chemical Homeostasis
Cellular Response To Toxic Substance
Regulation Of Excretion
Ion Homeostasis
Regulation Of Sensory Perception Of Pain
Mitochondrion Degradation
Regulation Of Protein Oligomerization
Regulation Of Sodium Ion Transmembrane Transporter Activity
Protein Import Into Nucleus, Translocation
Endosome To Lysosome Transport
Regulation Of Ion Transport
Bile Acid And Bile Salt Transport
Regulation Of Mitochondrial Membrane Potential
Regulation Of Sodium Ion Transmembrane Transport
Cytoplasmic Transport
G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Positive Regulation Of Cytosolic Calcium Ion Concentration
Synaptic Transmission
Cytosolic Calcium Ion Homeostasis
Regulation Of Smooth Muscle Contraction
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Cellular Response To Stimulus
Cellular Metal Ion Homeostasis
Cell-cell Signaling
Positive Regulation Of Smooth Muscle Contraction
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Signaling
Signal Transduction
Metal Ion Homeostasis
Cell Communication
Blood Circulation
Cellular Chemical Homeostasis
Ion Homeostasis
Response To Stimulus
Neuropeptide Signaling Pathway
Regulation Of Muscle Contraction
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Cellular Homeostasis
Chemical Homeostasis
Regulation Of Blood Pressure
Tachykinin Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure
Opioid Receptor Signaling Pathway
Regulation Of Vasoconstriction
Positive Regulation Of Uterine Smooth Muscle Contraction
Neurological System Process
Homeostatic Process
Regulation Of Cellular Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Blood Pressure
Behavior
Regulation Of CAMP Biosynthetic Process
Sensory Perception Of Pain
Regulation Of Secretion
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway
Regulation Of CAMP Metabolic Process
Response To Abiotic Stimulus
Regulation Of Adenylate Cyclase Activity
Tagcloud
?
anomalies
behind
bioinformatics
cart
ctf
dependence
depicting
ebpbeta
elaborate
govern
instance
intron
likewise
modify
nfya
nutshell
pdyn
pdyns
pharmaceutical
prodynorphin
prompting
regimes
retrieve
snps
tbp
usf
usf2
vdr
vulnerability
Tagcloud (Difference)
?
anomalies
behind
bioinformatics
cart
ctf
dependence
depicting
ebpbeta
elaborate
govern
instance
intron
likewise
modify
nfya
nutshell
pdyn
pdyns
pharmaceutical
prodynorphin
prompting
regimes
retrieve
snps
tbp
usf
usf2
vdr
vulnerability
Tagcloud (Intersection)
?