OPRK1

Gene Name		opioid receptor, kappa 1
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection
	Molecular Function	Opioid Receptor Activity Protein Binding Dynorphin Receptor Activity Neuropeptide Binding
	Biological Process	Immune Response Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Synaptic Transmission Sensory Perception Behavior Locomotory Behavior Sensory Perception Of Pain Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Opioid Receptor Signaling Pathway Regulation Of Saliva Secretion Defense Response To Virus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Tramadol Morphine Codeine Amitriptyline Hydromorphone Mirtazapine Meperidine Oxycodone Butorphanol Propoxyphene Pentazocine Naltrexone Sufentanil Fentanyl Menthol Loperamide Nalbuphine Levorphanol Remifentanil Buprenorphine Naloxone Dezocine 3-Methylthiofentanyl Heroin Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl Tapentadol Alvimopan Methylnaltrexone
Diseases
GWAS
Protein-protein Interactions		5 interactors: GABARAPL1 GNA15 GPRASP1 OPRD1 SLC9A3R1
Entrez ID		4986
HPRD ID		01309
Ensembl ID		ENSG00000082556
Uniprot IDs		P41145
PDB IDs		2A0D 2IQN 4DJH
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Dopamine Receptor Signaling Pathway Renal Phosphate Ion Absorption Glutathione Transport G-protein Coupled Receptor Catabolic Process Negative Regulation Of Sodium:proton Antiporter Activity Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway Renal Sodium Ion Transport G-protein Coupled Receptor Signaling Pathway Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Oligomerization Bile Acid Secretion Opioid Receptor Signaling Pathway Oligopeptide Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Renal Absorption Regulation Of Proton Transport Phosphate Ion Homeostasis G-protein Coupled Acetylcholine Receptor Signaling Pathway Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Cellular Ion Homeostasis Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of CREB Transcription Factor Activity Receptor Catabolic Process Nucleophagy Cellular Chemical Homeostasis Cellular Response To Toxic Substance Regulation Of Excretion Ion Homeostasis Regulation Of Sensory Perception Of Pain Mitochondrion Degradation Regulation Of Protein Oligomerization Regulation Of Sodium Ion Transmembrane Transporter Activity Protein Import Into Nucleus, Translocation Endosome To Lysosome Transport Regulation Of Ion Transport Bile Acid And Bile Salt Transport Regulation Of Mitochondrial Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Cytoplasmic Transport
Tagcloud ?		anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nfya nutshell pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp usf usf2 vdr vulnerability