NEDD9 and RFX6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NEDD9	RFX6
Gene Name		neural precursor cell expressed, developmentally down-regulated 9	regulatory factor X, 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Golgi Apparatus Spindle Focal Adhesion Cell Cortex Lamellipodium	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Cytoskeleton Organization Mitotic Nuclear Division Cell Adhesion Signal Transduction Integrin-mediated Signaling Pathway Regulation Of Growth Actin Filament Bundle Assembly Cell Division	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Endocrine Pancreas Development Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation
Pathways
Drugs
Diseases
GWAS		HIV-1 susceptibility ( 22174851)	Prostate cancer ( 20676098)
Protein-Protein Interactions		40 interactors: ABL1 APP BANP BCAR1 BCAR3 CDH1 CHAT CRK CRKL DIMT1 ELSPBP1 FYN ID2 ITCH LCK LYN MICAL1 NAB2 NCK1 NFKBIA NOTCH3 PIK3CA PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 TCF3 TRIM27 TRIP6 ZYX	25 interactors: AES ARNT2 CATSPER1 CCNK CYFIP1 DGCR6 DTX2 ESR2 FHL3 FRS3 KIF1A LMO3 NEDD9 PITX1 PLEKHN1 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 VPS37C
Entrez ID		4739	222546
HPRD ID		11888	11490
Ensembl ID		ENSG00000111859	ENSG00000185002
Uniprot IDs		Q14511	Q8HWS3
PDB IDs		2L81
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Immune System Process Innate Immune Response Response To Organonitrogen Compound Cell Activation Regulation Of Signal Transduction Regulation Of Immune Response Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Immune System Process Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Communication Cellular Response To Organonitrogen Compound Immune Response-regulating Signaling Pathway Regulation Of Metabolic Process Cellular Response To Organic Substance Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Immune System Process Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Response To Organic Substance Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Protein Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Immune Response Positive Regulation Of Protein Modification Process Regulation Of Protein Kinase Activity Neurotrophin Signaling Pathway Defense Response	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Energy Homeostasis Cellular Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Glycolytic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Fatty Acid Homeostasis Transcription From RNA Polymerase II Promoter Epithelial Cell Maturation Nitrogen Compound Metabolic Process Biosynthetic Process Histone-serine Phosphorylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Negative Regulation Of TOR Signaling Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Spliceosomal SnRNP Assembly Histone Phosphorylation Multicellular Organismal Development Sterol Biosynthetic Process Anion Homeostasis Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Cellular Response To Extracellular Stimulus Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of TOR Signaling Cellular Component Assembly Type B Pancreatic Cell Maturation Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Necroptotic Process Positive Regulation Of Cellular Metabolic Process Wnt Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Branchiomeric Skeletal Muscle Development Negative Regulation Of Glucose Import In Response To Insulin Stimulus
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	779a agenesis allelic annular atresia awaiting bi biliary cholestatic clues diarrhea duodenal enteroendocrine exome exploratory gallbladder hypoplasia intolerance jaundice jejunal k260t lys260thr malrotation missense monogenic necessitated neonatal pointed splice
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	779a agenesis allelic annular atresia awaiting bi biliary cholestatic clues diarrhea duodenal enteroendocrine exome exploratory gallbladder hypoplasia intolerance jaundice jejunal k260t lys260thr malrotation missense monogenic necessitated neonatal pointed splice
Tagcloud (Intersection) ?