RFX6 and STK16

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RFX6	STK16
Gene Name		regulatory factor X, 6	serine/threonine kinase 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Golgi-associated Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Endocrine Pancreas Development Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation	Regulation Of Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 20676098)
Protein-Protein Interactions		25 interactors: AES ARNT2 CATSPER1 CCNK CYFIP1 DGCR6 DTX2 ESR2 FHL3 FRS3 KIF1A LMO3 NEDD9 PITX1 PLEKHN1 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 VPS37C	47 interactors: ADAMTSL4 AES ALS2CR12 CALCOCO2 CCDC33 CRX CSNK2B DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FAM154A IKZF3 INCA1 KCTD14 KCTD17 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP26-1 MBP MEOX2 MGAT5B MIIP MTUS2 NAGK NIF3L1 NOTCH2NL PCSK5 PLSCR1 PLSCR3 REL RFX6 RPIA SKIL SPRY2 TCF12 TCF4 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6
Entrez ID		222546	8576
HPRD ID		11490	05281
Ensembl ID		ENSG00000185002	ENSG00000115661
Uniprot IDs		Q8HWS3	O75716
PDB IDs			2BUJ
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Energy Homeostasis Cellular Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Glycolytic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Fatty Acid Homeostasis Transcription From RNA Polymerase II Promoter Epithelial Cell Maturation Nitrogen Compound Metabolic Process Biosynthetic Process Histone-serine Phosphorylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Negative Regulation Of TOR Signaling Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Spliceosomal SnRNP Assembly Histone Phosphorylation Multicellular Organismal Development Sterol Biosynthetic Process Anion Homeostasis Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Cellular Response To Extracellular Stimulus Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of TOR Signaling Cellular Component Assembly Type B Pancreatic Cell Maturation Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Necroptotic Process Positive Regulation Of Cellular Metabolic Process Wnt Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Branchiomeric Skeletal Muscle Development Negative Regulation Of Glucose Import In Response To Insulin Stimulus	Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Immune System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Organic Substance Positive Regulation Of Cell Death Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Phospholipid Scrambling Regulation Of Nitrogen Compound Metabolic Process Gene Expression Positive Regulation Of Apoptotic Process Regulation Of Signaling Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Oligomerization Regulation Of Transcription, DNA-templated Negative Regulation Of Kinase Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Protein Homooligomerization Developmental Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Cell Death Death
Tagcloud ?		779a agenesis allelic annular atresia awaiting bi biliary cholestatic clues diarrhea duodenal enteroendocrine exome exploratory gallbladder hypoplasia intolerance jaundice jejunal k260t lys260thr malrotation missense monogenic necessitated neonatal pointed splice
Tagcloud (Difference) ?		779a agenesis allelic annular atresia awaiting bi biliary cholestatic clues diarrhea duodenal enteroendocrine exome exploratory gallbladder hypoplasia intolerance jaundice jejunal k260t lys260thr malrotation missense monogenic necessitated neonatal pointed splice
Tagcloud (Intersection) ?