NEDD9 and PRR20A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NEDD9	PRR20A
Description		neural precursor cell expressed, developmentally down-regulated 9	proline rich 20A
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Immunological Synapse Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cilium Cell Cortex Membrane Basolateral Plasma Membrane Lamellipodium Ciliary Basal Body Cell Projection Anchoring Junction Mitotic Spindle
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Learning Or Memory Cell Migration Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Osteoclast Differentiation Actin Filament Bundle Assembly Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Cilium Disassembly Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Dendritic Spine Maintenance Positive Regulation Of Protein Localization Positive Regulation Of Immunological Synapse Formation
Pathways
Drugs
Diseases
GWAS		Childhood dental caries in permanent teeth ( 29931343) Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) HIV-1 susceptibility ( 22174851) Macular thickness ( 30535121) Prostate cancer ( 25217961) Small cell lung carcinoma ( 28604730)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Left ventricular end-diastolic volume (MTAG) ( 33495596) Left ventricular end-systolic volume (MTAG) ( 33495596) Left ventricular mass (MTAG) ( 33495596) Systolic blood pressure ( 30224653) Total cholesterol levels ( 33339817)
Interacting Genes		70 interacting genes: ABL1 ACTMAP ANKS1A APP AURKA BANP BCAR1 BCAR3 CDC42EP2 CDH1 CHAT CRK CRKL DIMT1 DMRTB1 DOCK9 DPPA4 EEIG1 ELSPBP1 EXOSC8 FAM168B FOSB FYN FZR1 HOXA1 ID2 INCA1 ITCH KLHL20 KRT32 LCK LHX8 LYN MED19 MICAL1 NAB2 NBPF19 NCK1 NFKBIA NOTCH2NLA NOTCH3 PEX14 PIK3CA PIK3R3 PRAM1 PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 SNAPIN TBX19 TCF3 TFCP2 TRAF2 TRIM23 TRIM27 TRIP6 WWOX ZNF76 ZYX	95 interacting genes: ABI2 ANKHD1 ARID5A ATXN1 BANP BEND2 BHLHE40 BICRAL C10orf55 C1orf94 C3orf36 CABP2 CCNK CDC37 CELF4 DAB1 DAZAP2 DMRT3 DVL3 EIF4ENIF1 ESRP1 FAM168A FAM222B FAM9A FOXH1 FOXP3 GATA2 GLIS2 GTF2A1 HIVEP1 HLX HYPK KRTAP19-1 KRTAP19-5 LASP1 MAGED1 MBNL3 NAA38 NCK2 NEDD9 NOTCH3 NTAQ1 OXER1 PATZ1 PHF1 PITX1 POGZ POU6F2 PRR20B PRR20C PRR20D PRR20E PRR34 PRR35 PTTG2 RBFOX1 RBM10 RBM23 RBM42 RBPMS RBPMS2 RHOXF2 RIPPLY1 RNF4 ROR2 SAMD11 SELENOV SH3RF1 SMAP1 SNRPB SNRPC SOX5 SP4 SRPK2 TBX3 TBX6 TCF7L2 TFG THAP1 TIAL1 TLX3 TOLLIP TPRX1 TRIM35 VAC14 VENTX VEZF1 VPS37C YPEL3 ZBTB32 ZC3H10 ZCCHC14 ZNF385C ZNF488 ZNF683
Entrez ID		4739	122183
HPRD ID		11888	13445
Ensembl ID		ENSG00000111859	ENSG00000204919
Uniprot IDs		A0A087WUD2 Q14511	P86478 P86479 P86480 P86481 P86496
PDB IDs		2L81 5X3S
Enriched GO Terms of Interacting Partners?		Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Phosphotyrosine Residue Binding Ephrin Receptor Binding Ephrin Receptor Signaling Pathway Cytosol Cell Surface Receptor Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Macromolecule Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Leukocyte Activation Cell Activation Positive Regulation Of Metabolic Process T Cell Receptor Signaling Pathway Cell Migration Response To Transforming Growth Factor Beta Signal Complex Assembly Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Positive Regulation Of RNA Biosynthetic Process ERBB Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of Immune Response Lymphocyte Activation Intracellular Signaling Cassette Immune System Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Intracellular Signal Transduction Endothelin Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Integrin-mediated Signaling Pathway DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Cell Motility Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Nucleus Signal Transduction Regulation Of Metabolic Process	Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Chromatin Protein Binding Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding Positive Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Negative Regulation Of Biosynthetic Process RNA Splicing Sequence-specific DNA Binding Cell Fate Commitment Nucleoplasm MRNA Binding Myoblast Fate Commitment Regulation Of Neuron Differentiation Regulation Of Developmental Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding
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