NEDD9 and ELSPBP1

Number of citations of the paper that reports this interaction (PubMedID 10502414)
0

Data Source:
HPRD (two hybrid)

		NEDD9	ELSPBP1
Description		neural precursor cell expressed, developmentally down-regulated 9	epididymal sperm binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Immunological Synapse Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cilium Cell Cortex Membrane Basolateral Plasma Membrane Lamellipodium Ciliary Basal Body Cell Projection Anchoring Junction Mitotic Spindle	Extracellular Region Cell Surface
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding	Heparin Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Learning Or Memory Cell Migration Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Osteoclast Differentiation Actin Filament Bundle Assembly Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Cilium Disassembly Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Dendritic Spine Maintenance Positive Regulation Of Protein Localization Positive Regulation Of Immunological Synapse Formation	Single Fertilization Sperm Capacitation
Pathways
Drugs			N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium
Diseases
GWAS		Childhood dental caries in permanent teeth ( 29931343) Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) HIV-1 susceptibility ( 22174851) Macular thickness ( 30535121) Prostate cancer ( 25217961) Small cell lung carcinoma ( 28604730)	Intelligence ( 22449649) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Refractive error ( 32231278)
Interacting Genes		70 interacting genes: ABL1 ACTMAP ANKS1A APP AURKA BANP BCAR1 BCAR3 CDC42EP2 CDH1 CHAT CRK CRKL DIMT1 DMRTB1 DOCK9 DPPA4 EEIG1 ELSPBP1 EXOSC8 FAM168B FOSB FYN FZR1 HOXA1 ID2 INCA1 ITCH KLHL20 KRT32 LCK LHX8 LYN MED19 MICAL1 NAB2 NBPF19 NCK1 NFKBIA NOTCH2NLA NOTCH3 PEX14 PIK3CA PIK3R3 PRAM1 PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 SNAPIN TBX19 TCF3 TFCP2 TRAF2 TRIM23 TRIM27 TRIP6 WWOX ZNF76 ZYX	4 interacting genes: MYOD1 NEDD9 PSMD9 TAL1
Entrez ID		4739	64100
HPRD ID		11888	12119
Ensembl ID		ENSG00000111859	ENSG00000169393
Uniprot IDs		A0A087WUD2 Q14511	A0A384NKL6 Q96BH3
PDB IDs		2L81 5X3S
Enriched GO Terms of Interacting Partners?		Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Phosphotyrosine Residue Binding Ephrin Receptor Binding Ephrin Receptor Signaling Pathway Cytosol Cell Surface Receptor Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Macromolecule Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Leukocyte Activation Cell Activation Positive Regulation Of Metabolic Process T Cell Receptor Signaling Pathway Cell Migration Response To Transforming Growth Factor Beta Signal Complex Assembly Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Positive Regulation Of RNA Biosynthetic Process ERBB Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of Immune Response Lymphocyte Activation Intracellular Signaling Cassette Immune System Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Intracellular Signal Transduction Endothelin Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Integrin-mediated Signaling Pathway DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Cell Motility Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Nucleus Signal Transduction Regulation Of Metabolic Process	BHLH Transcription Factor Binding E-box Binding Transcription Regulator Complex Protein Dimerization Activity Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cellular Component Organization Myoblast Fate Determination Positive Regulation Of SnRNA Transcription By RNA Polymerase II Regulation Of Cell Development Skeletal Muscle Fiber Adaptation Negative Regulation Of Myoblast Proliferation Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Cell Differentiation Cell Fate Commitment Myotube Differentiation Involved In Skeletal Muscle Regeneration RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Myeloid Cell Differentiation Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Dendritic Spine Maintenance Positive Regulation Of Immunological Synapse Formation Positive Regulation Of Myeloid Cell Differentiation Proteasome Regulatory Particle Assembly Regulation Of Mast Cell Differentiation Hemangioblast Cell Differentiation Positive Regulation Of Chromatin Organization Basophil Differentiation Astrocyte Fate Commitment Positive Regulation Of Metabolic Process Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Developmental Process Transcription By RNA Polymerase II Glial Cell Fate Commitment Regulation Of Multicellular Organismal Development Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Skeletal Muscle Fiber Development Regulation Of Cell Differentiation Cilium Disassembly Proteasome Regulatory Particle, Base Subcomplex Proteasome Regulatory Particle Spinal Cord Association Neuron Differentiation Regulation Of Somatic Stem Cell Population Maintenance Regulation Of Dendritic Spine Maintenance Megakaryocyte Differentiation Enzyme Binding Muscle Cell Fate Commitment Proteasome Assembly Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription
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