NEB and MYPN

Number of citations of the paper that reports this interaction (PMID 11309420)
43

Data Source:
HPRD (in vitro, two hybrid)

		NEB	MYPN
Gene Name		nebulin	myopalladin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Vesicular Exosome	Nucleus Z Disc I Band
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length	Sarcomere Organization
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS			Optic disc size (disc) ( 20395239)
Protein-Protein Interactions		14 interactors: ABI1 ACTN4 APC CALM1 DES KLHL40 MYPN TMOD1 TMOD4 TRIM55 TRIM63 TTN XIRP1 XIRP2	7 interactors: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL TTN
Entrez ID		4703	84665
HPRD ID		01196	10536
Ensembl ID		ENSG00000183091	ENSG00000138347
Uniprot IDs		P20929 Q05C45 Q14214 Q96MF8	Q86TC9
PDB IDs		1ARK 1NEB
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Cytoskeleton Organization Actin Cytoskeleton Organization Myofibril Assembly Muscle Contraction Striated Muscle Cell Differentiation Actomyosin Structure Organization Muscle System Process Muscle Structure Development Muscle Cell Differentiation Striated Muscle Cell Development Muscle Cell Development Organelle Organization Actin Filament Organization Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Sarcomere Organization Organelle Assembly Actin Filament-based Movement Platelet Degranulation Anatomical Structure Formation Involved In Morphogenesis Negative Regulation Of Protein Complex Disassembly Anatomical Structure Morphogenesis Pointed-end Actin Filament Capping Striated Muscle Tissue Development Regulation Of Protein Depolymerization Cell Development Muscle Tissue Development Cellular Component Assembly Regulation Of Protein Complex Disassembly Anatomical Structure Development Negative Regulation Of Cytoskeleton Organization Developmental Process Cardiac Muscle Tissue Development Platelet Activation Cell Differentiation Cell-cell Junction Organization Tissue Development Tight Junction Assembly Actin Filament Capping Positive Regulation Of Ion Transmembrane Transporter Activity Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Transporter Activity Cell Activation Muscle Organ Development Negative Regulation Of Actin Filament Depolymerization Muscle Tissue Morphogenesis Regulation Of Protein Kinase Activity Organ Development	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Actin Filament-based Process Muscle Contraction Muscle System Process Myofibril Assembly Response To Muscle Stretch Actomyosin Structure Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Response To Mechanical Stimulus Striated Muscle Cell Differentiation Focal Adhesion Assembly Muscle Organ Development Cellular Component Assembly Striated Muscle Tissue Development Adherens Junction Assembly Muscle Cell Differentiation Muscle Tissue Development Cell-substrate Junction Assembly Sarcomere Organization Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Muscle Organ Morphogenesis Platelet Degranulation Organelle Assembly Adherens Junction Organization Cardiac Muscle Thin Filament Assembly Heart Development Cardiac Muscle Cell Differentiation Movement Of Cell Or Subcellular Component Actin Cytoskeleton Organization Cardiocyte Differentiation Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Cell-matrix Adhesion Directional Locomotion Platelet Activation Myosin Filament Assembly Cell Junction Assembly Cardiovascular System Development Cell-cell Junction Organization Cell-substrate Adhesion
Tagcloud ?		accounts adds adolescence adulthood behavioural chaotic circadian compulsive conflictful conflicting daytime eaters eating eighty employment exploratory highlighted interviewed mood nes night obesity perceptions rhythm solitary standing thematic uncontrolled unemployed
Tagcloud (Difference) ?		accounts adds adolescence adulthood behavioural chaotic circadian compulsive conflictful conflicting daytime eaters eating eighty employment exploratory highlighted interviewed mood nes night obesity perceptions rhythm solitary standing thematic uncontrolled unemployed
Tagcloud (Intersection) ?