NEB and TMOD1

Number of citations of the paper that reports this interaction (PMID 11016930)
40

Data Source:
HPRD (in vivo, in vitro)

		NEB	TMOD1
Gene Name		nebulin	tropomodulin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Actin Cytoskeleton Z Disc Extracellular Vesicular Exosome	Cytosol Striated Muscle Thin Filament COP9 Signalosome Membrane Cortical Cytoskeleton
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	Tropomyosin Binding Actin Filament Binding
	Biological Process	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Muscle Filament Sliding Myofibril Assembly Pointed-end Actin Filament Capping
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Protein-Protein Interactions		14 interactors: ABI1 ACTN4 APC CALM1 DES KLHL40 MYPN TMOD1 TMOD4 TRIM55 TRIM63 TTN XIRP1 XIRP2	4 interactors: NEB PRKAA2 TMSB10 TPM3
Entrez ID		4703	7111
HPRD ID		01196	01838
Ensembl ID		ENSG00000183091	ENSG00000136842
Uniprot IDs		P20929 Q05C45 Q14214 Q96MF8	P28289 Q5T7W3
PDB IDs		1ARK 1NEB
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Cytoskeleton Organization Actin Cytoskeleton Organization Myofibril Assembly Muscle Contraction Striated Muscle Cell Differentiation Actomyosin Structure Organization Muscle System Process Muscle Structure Development Muscle Cell Differentiation Striated Muscle Cell Development Muscle Cell Development Organelle Organization Actin Filament Organization Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Sarcomere Organization Organelle Assembly Actin Filament-based Movement Platelet Degranulation Anatomical Structure Formation Involved In Morphogenesis Negative Regulation Of Protein Complex Disassembly Anatomical Structure Morphogenesis Pointed-end Actin Filament Capping Striated Muscle Tissue Development Regulation Of Protein Depolymerization Cell Development Muscle Tissue Development Cellular Component Assembly Regulation Of Protein Complex Disassembly Anatomical Structure Development Negative Regulation Of Cytoskeleton Organization Developmental Process Cardiac Muscle Tissue Development Platelet Activation Cell Differentiation Cell-cell Junction Organization Tissue Development Tight Junction Assembly Actin Filament Capping Positive Regulation Of Ion Transmembrane Transporter Activity Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Transporter Activity Cell Activation Muscle Organ Development Negative Regulation Of Actin Filament Depolymerization Muscle Tissue Morphogenesis Regulation Of Protein Kinase Activity Organ Development	Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Actin Filament-based Process Regulation Of Actin Filament Length Muscle Contraction Muscle System Process Regulation Of Cellular Component Size Carnitine Shuttle Regulation Of Actin Cytoskeleton Organization Somatic Muscle Development Sequestering Of Actin Monomers Regulation Of Actin Filament-based Process Carnitine Transmembrane Transport Regulation Of Energy Homeostasis Carnitine Transport Positive Regulation Of Glycolytic Process Fatty Acid Homeostasis Regulation Of Cytoskeleton Organization Quaternary Ammonium Group Transport Histone-serine Phosphorylation Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Negative Regulation Of TOR Signaling Regulation Of Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Long-chain Fatty Acid Transport Histone Phosphorylation Ammonium Transmembrane Transport Sterol Biosynthetic Process Anion Homeostasis Regulation Of Organelle Organization
Tagcloud ?		accounts adds adolescence adulthood behavioural chaotic circadian compulsive conflictful conflicting daytime eaters eating eighty employment exploratory highlighted interviewed mood nes night obesity perceptions rhythm solitary standing thematic uncontrolled unemployed	assembly capping contractile contraction depolymerization ends filament leiomodins lmod1 lmod3 lmods localize locomotion myofibril myofibrillogenesis nucleators pointed redundantly rescued sarcomere structurally supplemented thin tmod4 tropomodulin unexpectedly uniformity xenopus
Tagcloud (Difference) ?		accounts adds adolescence adulthood behavioural chaotic circadian compulsive conflictful conflicting daytime eaters eating eighty employment exploratory highlighted interviewed mood nes night obesity perceptions rhythm solitary standing thematic uncontrolled unemployed	assembly capping contractile contraction depolymerization ends filament leiomodins lmod1 lmod3 lmods localize locomotion myofibril myofibrillogenesis nucleators pointed redundantly rescued sarcomere structurally supplemented thin tmod4 tropomodulin unexpectedly uniformity xenopus
Tagcloud (Intersection) ?