TMOD1 and TMSB10

Number of citations of the paper that reports this interaction (PMID 14741341)
3

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TMOD1	TMSB10
Gene Name		tropomodulin 1	thymosin beta 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Striated Muscle Thin Filament COP9 Signalosome Membrane Cortical Cytoskeleton	Cytoplasm Cytoskeleton
	Molecular Function	Tropomyosin Binding Actin Filament Binding	Actin Monomer Binding
	Biological Process	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Muscle Filament Sliding Myofibril Assembly Pointed-end Actin Filament Capping	Actin Filament Organization Sequestering Of Actin Monomers
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Protein-Protein Interactions		4 interactors: NEB PRKAA2 TMSB10 TPM3	7 interactors: ALAS1 KRTAP9-2 POT1 TERF1 TERF2 TERF2IP TMOD1
Entrez ID		7111	9168
HPRD ID		01838	01779
Ensembl ID		ENSG00000136842	ENSG00000034510
Uniprot IDs		P28289 Q5T7W3	P63313
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Actin Filament-based Process Regulation Of Actin Filament Length Muscle Contraction Muscle System Process Regulation Of Cellular Component Size Carnitine Shuttle Regulation Of Actin Cytoskeleton Organization Somatic Muscle Development Sequestering Of Actin Monomers Regulation Of Actin Filament-based Process Carnitine Transmembrane Transport Regulation Of Energy Homeostasis Carnitine Transport Positive Regulation Of Glycolytic Process Fatty Acid Homeostasis Regulation Of Cytoskeleton Organization Quaternary Ammonium Group Transport Histone-serine Phosphorylation Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Negative Regulation Of TOR Signaling Regulation Of Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Positive Regulation Of Autophagy Long-chain Fatty Acid Transport Histone Phosphorylation Ammonium Transmembrane Transport Sterol Biosynthetic Process Anion Homeostasis Regulation Of Organelle Organization	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Telomere Capping Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Chromosome Organization Telomeric Loop Formation Age-dependent Telomere Shortening Negative Regulation Of DNA Replication Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere DNA Replication Regulation Of Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Replicative Cell Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Regulation Of DNA Replication Regulation Of Telomerase Activity Organelle Organization Negative Regulation Of DNA Biosynthetic Process Regulation Of Cellular Component Organization Protein Localization To Chromosome Chromosome Organization DNA Metabolic Process Regulation Of DNA Biosynthetic Process Positive Regulation Of Organelle Organization Cell Aging Homeostatic Process Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of DNA Metabolic Process Telomere Formation Via Telomerase Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Helicase Activity Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		assembly capping contractile contraction depolymerization ends filament leiomodins lmod1 lmod3 lmods localize locomotion myofibril myofibrillogenesis nucleators pointed redundantly rescued sarcomere structurally supplemented thin tmod4 tropomodulin unexpectedly uniformity xenopus	acidic arrest chemoresistance coil coiled diminished dramatically ep2 g2 hela inactivated mediating mmp9 mtacc mtacc3 overexpressed paclitaxel pecam plk ppia prostaglandin proteome rab31 synergistic tacc tacc3 transactivation transforming uhrf1
Tagcloud (Difference) ?		assembly capping contractile contraction depolymerization ends filament leiomodins lmod1 lmod3 lmods localize locomotion myofibril myofibrillogenesis nucleators pointed redundantly rescued sarcomere structurally supplemented thin tmod4 tropomodulin unexpectedly uniformity xenopus	acidic arrest chemoresistance coil coiled diminished dramatically ep2 g2 hela inactivated mediating mmp9 mtacc mtacc3 overexpressed paclitaxel pecam plk ppia prostaglandin proteome rab31 synergistic tacc tacc3 transactivation transforming uhrf1
Tagcloud (Intersection) ?