TMOD1 and TMSB10

Number of citations of the paper that reports this interaction (PubMedID 14741341)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TMOD1	TMSB10
Description		tropomodulin 1	thymosin beta 10
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament COP9 Signalosome Membrane Myofibril Sarcomere Cortical Cytoskeleton	Cytoplasm Cytoskeleton
	Molecular Function	Actin Binding Tropomyosin Binding	Actin Binding Actin Monomer Binding Protein Binding Protein Sequestering Activity
	Biological Process	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Myofibril Assembly Pointed-end Actin Filament Capping Lens Fiber Cell Development	Actin Filament Organization Regulation Of Cell Migration
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intracranial aneurysm ( 30823506) Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937) Zinc levels ( 26025379)
Interacting Genes		16 interacting genes: APC BUB1 CDH1 CDKN2A DCC DLC1 FBXL17 FBXW7 MLH3 NEB ODC1 PIK3CA PRKAA2 TLR2 TMSB10 TPM3	8 interacting genes: ALAS1 KRTAP9-2 POT1 SRPK2 TERF1 TERF2 TERF2IP TMOD1
Entrez ID		7111	9168
HPRD ID		01838	01779
Ensembl ID		ENSG00000136842	ENSG00000034510
Uniprot IDs		P28289	P63313
PDB IDs		4PKG 4PKH 4PKI 4Z8G 4Z94 8F8T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization Regulation Of Protein Localization Regulation Of Cellular Component Organization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Gamma-catenin Binding Regulation Of Cytoskeleton Organization Apoptotic Process Negative Regulation Of Cell Development Cell Death Programmed Cell Death Negative Regulation Of Cytoskeleton Organization Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Cell Communication Negative Regulation Of Supramolecular Fiber Organization Catenin Complex Regulation Of Protein Catabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signaling Cytosol Postsynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Nervous System Development Regulation Of Organelle Organization Negative Regulation Of Cell Growth Negative Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell-matrix Adhesion Lamellipodium Sister Chromatid Cohesion Regulation Of Macroautophagy Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity Cellular Response To Oxygen-containing Compound Carbohydrate Homeostasis Glucose Homeostasis Regulation Of Protein Targeting To Mitochondrion Ligase Inhibitor Activity Supramolecular Fiber Organization Triacyl Lipopeptide Binding Regulation Of Mitotic Cell Cycle Negative Regulation Of Growth Negative Regulation Of Axonogenesis Regulation Of Apoptotic Process Cytoplasm Positive Regulation Of Apoptotic Process Regulation Of Establishment Of Protein Localization	Shelterin Complex Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Telomere Capping RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Telomeric D-loop Disassembly Telomeric Loop Disassembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Telomere Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromosome, Telomeric Region Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Chromosome Organization Telomerase Activity Protection From Non-homologous End Joining At Telomere Positive Regulation Of DNA Metabolic Process Chromosome Negative Regulation Of Cellular Component Organization Regulation Of DNA Biosynthetic Process Double-stranded Telomeric DNA Binding Chromosome Organization Protein Localization To Chromosome, Telomeric Region Telomere Maintenance In Response To DNA Damage Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Organelle Organization Regulation Of DNA Repair Macromolecule Biosynthetic Process DNA Metabolic Process Organelle Organization Negative Regulation Of DNA Recombination Male Germ Cell Nucleus Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
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