MPP2 and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		MPP2	ERBB2IP
Gene Name		membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	erbb2 interacting protein
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Guanylate Kinase Activity PDZ Domain Binding	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Signal Transduction Nucleotide Phosphorylation	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways			Signaling by ERBB2
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CSNK2B DLG1 ERBB2IP LIN7A PLK1	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		4355	55914
HPRD ID		02837	06090
Ensembl ID		ENSG00000108852	ENSG00000112851
Uniprot IDs		B4DGE9 B4DRJ0 B4DZ84 B7Z3G8 D3DX48 D3DX49 E7EV91 Q14168	B4DIP2 Q96RT1
PDB IDs		2E7K	1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Cell Polarity Asymmetric Protein Localization Cell Cycle Cellular Protein Localization Endomembrane System Organization Protein Localization Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Kinase Activity Protein Localization To Plasma Membrane Basal Protein Localization Activation Of APC-Cdc20 Complex Activity Membrane Organization Positive Regulation Of Phosphorylation Mitotic Cell Cycle Checkpoint Cellular Localization Positive Regulation Of Protein Modification Process Polar Body Extrusion After Meiotic Divisions Regulation Of Protein Phosphorylation Negative Regulation Of Mitotic Cell Cycle Plasma Membrane Organization Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Protein Localization To Basolateral Plasma Membrane T Cell Cytokine Production Cytoskeleton Organization Regulation Of Binding Hard Palate Development Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Protein Metabolic Process Activation Of Anaphase-promoting Complex Activity Maintenance Of Apical/basal Cell Polarity Meiotic Cytokinesis Regulation Of Phosphorylation Positive Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Metaphase/anaphase Transition Of Mitotic Cell Cycle Receptor Localization To Synapse Peristalsis Cytokine Production Involved In Immune Response Immunological Synapse Formation Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Endothelial Tube Morphogenesis Protein Localization To Membrane Protein Localization To Chromatin	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		clusters coordinated correlates dmrs exploration hematopoietic hierarchy highlight hsc hscs integrated inversely isoform landscape lncrnas loci methylated methylome multipotency multipotent operating proteome resource signature steps top transcript transcriptome unexpectedly	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		clusters coordinated correlates dmrs exploration hematopoietic hierarchy highlight hsc hscs integrated inversely isoform landscape lncrnas loci methylated methylome multipotency multipotent operating proteome resource signature steps top transcript transcriptome unexpectedly	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?