MET and PLCG1

  • Number of citations of the paper that reports this interaction (PMID 7513258)
  • 144
  • Data Source:
  • HPRD (in vitro)

MET

PLCG1

Gene Name MET proto-oncogene, receptor tyrosine kinase phospholipase C, gamma 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Multiple sclerosis (severity) ( 19010793)
Protein-Protein Interactions 37 interactors: BAG1 CASP3 CBL CNR1 CTNNB1 CTTN DAPK3 DCN DNAJA3 EGFR FAS GAB1 GLMN GRB2 HGF HGS INPP5D INPPL1 ITGB4 MUC20 PCBD2 PIK3R1 PLCG1 PLXNB1 PTPN11 PTPRB PTPRJ RANBP10 RANBP9 SHC1 SMC1A SNAPIN SNX2 SPSB1 SRC STAT3 VAV1 106 interactors: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GNB2L1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 4233 5335
HPRD ID 01280 01398
Ensembl ID ENSG00000105976 ENSG00000124181
Uniprot IDs B4DLF5 P08581 P19174 Q4LE43 Q9UFY1
PDB IDs 1FYR 1R0P 1R1W 1SHY 1SSL 1UX3 2G15 2RFN 2RFS 2UZX 2UZY 2WD1 2WGJ 2WKM 3A4P 3BUX 3C1X 3CCN 3CD8 3CE3 3CTH 3CTJ 3DKC 3DKF 3DKG 3EFJ 3EFK 3F66 3F82 3I5N 3L8V 3LQ8 3Q6U 3Q6W 3QTI 3R7O 3RHK 3U6H 3U6I 3VW8 3ZXZ 3ZZE 4AOI 4AP7 4DEG 4DEH 4DEI 4EEV 4GG5 4GG7 4K3J 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
basophil  basophils  c5a  ccr2  ccr3  chains  chemoattractant  chemotactic  continuous  continuously  cxcr1  cxcr2  eotaxin  express  fmlp  formyl  granulocyte  hardly  leu  leukotrienes  lt  ltc4  macrophage  mcp  mcp1  mediate  migratory  phe  unrelated  weakly 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Difference) ?
basophil  basophils  c5a  ccr2  ccr3  chains  chemoattractant  chemotactic  continuous  continuously  cxcr1  cxcr2  eotaxin  express  fmlp  formyl  granulocyte  hardly  leu  leukotrienes  lt  ltc4  macrophage  mcp  mcp1  mediate  migratory  phe  unrelated  weakly 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Intersection) ?