MAL and PTPRN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAL	PTPRN
Gene Name		mal, T-cell differentiation protein	protein tyrosine phosphatase, receptor type, N
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Endoplasmic Reticulum Integral Component Of Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft	Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Channel Activity Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath	Protein Tyrosine Phosphatase Activity Protein Binding Spectrin Binding GTPase Binding
	Biological Process	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Transmembrane Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Response To Reactive Oxygen Species Protein Dephosphorylation Response To Glucose Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Response To Estrogen Response To CAMP Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: EDA FIBCD1 KLRC1 LDLRAD1 LSMEM1 MYD88 PTPRN SMIM3 USP7	13 interactors: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4
Entrez ID		4118	5798
HPRD ID		01789	03466
Ensembl ID		ENSG00000172005	ENSG00000054356
Uniprot IDs		P21145	Q16849 Q96IA0
PDB IDs			2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Dense Core Granule Maturation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Fungal Origin Trachea Gland Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-23 Production Establishment Of Endothelial Intestinal Barrier Salivary Gland Cavitation Maintenance Of DNA Methylation Cellular Response To Stimulus Positive Regulation Of Interleukin-17 Production 3'-UTR-mediated MRNA Stabilization Type I Interferon Biosynthetic Process Positive Regulation Of Chemokine Biosynthetic Process Response To Peptidoglycan Toll Signaling Pathway Type I Interferon Production Cytokine-mediated Signaling Pathway Hair Follicle Placode Formation Histone Deubiquitination Positive Regulation Of NF-kappaB Import Into Nucleus Response To Stimulus Cytokine Biosynthetic Process Ectoderm Development MRNA Stabilization Negative Regulation Of Growth Of Symbiont In Host Cellular Response To Cytokine Stimulus Establishment Of Endothelial Barrier	Myoblast Fusion Central Nervous System Development Syncytium Formation Regulation Of Cellular Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Adult Walking Behavior Regulation Of Protein Metabolic Process Myotube Differentiation Cell Differentiation Muscle Cell Differentiation Regulation Of Sodium Ion Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Uncoating Of Virus Anatomical Structure Development Response To Stimulus Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Interaction With Host Spinal Cord Development Adult Locomotory Behavior Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Serotonin Uptake Membrane Raft Polarization Viral Release From Host Cell Developmental Process Muscle Structure Development Signaling Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of The Force Of Heart Contraction Regulation Of Generation Of L-type Calcium Current Cell Communication Regulation Of Neurotransmitter Levels Cell Maturation Myelination Peptidyl-cysteine S-nitrosylation Membrane Raft Localization Axon Ensheathment Regulation Of Adrenergic Receptor Signaling Pathway Age-dependent Response To Oxidative Stress Regulation Of Heart Contraction Adult Behavior Peptidyl-tyrosine Dephosphorylation
Tagcloud ?		100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Difference) ?		100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected	2j allen atlas b6 bc023892 btg3 bves drd5 edinger egr1 ew ewcp ewpg ghsr housekeeping microdissection neto1 neurogenetic neuropeptides oculomotor peptidergic postn preganglionic projecting publicly punch rcn1 ucn westphal
Tagcloud (Intersection) ?