MAL and SMIM3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAL	SMIM3
Gene Name		mal, T-cell differentiation protein	small integral membrane protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Endoplasmic Reticulum Integral Component Of Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft	Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Channel Activity Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Transmembrane Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: EDA FIBCD1 KLRC1 LDLRAD1 LSMEM1 MYD88 PTPRN SMIM3 USP7	8 interactors: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1
Entrez ID		4118	85027
HPRD ID		01789	12212
Ensembl ID		ENSG00000172005	ENSG00000256235
Uniprot IDs		P21145	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Dense Core Granule Maturation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Fungal Origin Trachea Gland Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-23 Production Establishment Of Endothelial Intestinal Barrier Salivary Gland Cavitation Maintenance Of DNA Methylation Cellular Response To Stimulus Positive Regulation Of Interleukin-17 Production 3'-UTR-mediated MRNA Stabilization Type I Interferon Biosynthetic Process Positive Regulation Of Chemokine Biosynthetic Process Response To Peptidoglycan Toll Signaling Pathway Type I Interferon Production Cytokine-mediated Signaling Pathway Hair Follicle Placode Formation Histone Deubiquitination Positive Regulation Of NF-kappaB Import Into Nucleus Response To Stimulus Cytokine Biosynthetic Process Ectoderm Development MRNA Stabilization Negative Regulation Of Growth Of Symbiont In Host Cellular Response To Cytokine Stimulus Establishment Of Endothelial Barrier	Bleb Assembly Inflammatory Response Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Carbohydrate Mediated Signaling Membrane Raft Polarization Activation Of Innate Immune Response Myelination Axon Ensheathment Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Membrane Raft Localization Positive Regulation Of Innate Immune Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Innate Immune Response Positive Regulation Of Protein Homodimerization Activity Spindle Midzone Assembly 3'-UTR-mediated MRNA Stabilization Cellular Response To Bacterial Lipopeptide T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Cell Projection Assembly Cell Death Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Microtubule Severing Lipid Particle Organization Leukocyte Cell-cell Adhesion Cellular Response To Lipoteichoic Acid Positive Regulation Of Interleukin-6 Biosynthetic Process Homotypic Cell-cell Adhesion Positive Regulation Of Transcription Via Serum Response Element Binding Apical Protein Localization Phagocytosis, Recognition Negative Regulation Of Lipid Catabolic Process Regulation Of Protein Homodimerization Activity Membrane Raft Organization Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Lymphocyte Activation Defense Response To Protozoan
Tagcloud ?		100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Difference) ?		100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Intersection) ?