MAG and COL2A1

Number of citations of the paper that reports this interaction (PMID 2446864)
8

Data Source:
HPRD (in vitro)

		MAG	COL2A1
Gene Name		myelin associated glycoprotein	collagen, type II, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Paranode Region Of Axon Schmidt-Lanterman Incisure	Extracellular Region Collagen Type II Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Carbohydrate Binding	Extracellular Matrix Structural Constituent Conferring Tensile Strength Identical Protein Binding Metal Ion Binding Platelet-derived Growth Factor Binding
	Biological Process	Cell Adhesion Blood Coagulation Substantia Nigra Development Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Leukocyte Migration	Skeletal System Development Cartilage Condensation Tissue Homeostasis Endochondral Ossification Chondrocyte Differentiation Heart Morphogenesis Proteoglycan Metabolic Process Axon Guidance Central Nervous System Development Visual Perception Sensory Perception Of Sound Regulation Of Gene Expression Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Fibril Organization Collagen Catabolic Process Notochord Development Inner Ear Morphogenesis Cartilage Development Palate Development Limb Bud Formation Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Otic Vesicle Development Cellular Response To BMP Stimulus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling Basigin interactions Cell surface interactions at the vascular wall	Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R	33 interactors: ANXA5 BGN BMP2 C1QA CHAD COL6A1 COL9A1 COL9A2 COL9A3 COMP DDR1 FGF7 FN1 HTRA1 HYAL1 ITGA2B LOXL4 MAG MATN1 MMP1 MMP13 PCOLCE PDGFA PDGFB PDIA2 PKD1 PRELP RELA SPARC TGFB1 TGFBI THBS1 TNFRSF10A
Entrez ID		4099	1280
HPRD ID		01160	00361
Ensembl ID		ENSG00000105695	ENSG00000139219
Uniprot IDs		P20916 Q53ES7	P02458
PDB IDs			1U5M 2FSE 2SEB
Enriched GO Terms of Interacting Partners?		Axon Development Cell Morphogenesis Involved In Differentiation Axonogenesis Extracellular Matrix Disassembly Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Generation Of Neurons Collagen Catabolic Process Neuron Projection Morphogenesis Neurogenesis Neuron Development Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Cell Morphogenesis Multicellular Organismal Metabolic Process Axon Guidance Neuron Differentiation Cell Projection Morphogenesis Cell Projection Organization Cell Part Morphogenesis Nervous System Development Cell Development Extracellular Matrix Organization Extracellular Structure Organization Movement Of Cell Or Subcellular Component Cell Differentiation Chemotaxis Locomotion Anatomical Structure Morphogenesis System Development Multicellular Organismal Development Anatomical Structure Development Response To External Stimulus Developmental Process Regulation Of Cell Development Regulation Of Neurogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Differentiation Regulation Of Neuron Differentiation Regulation Of Axonogenesis Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Organ Development Response To Stimulus Regulation Of Neuron Projection Development Central Nervous System Development Platelet Activation Regulation Of Cell Projection Organization Head Development Tissue Development	Extracellular Matrix Organization Extracellular Structure Organization Connective Tissue Development Cartilage Development Skeletal System Development Anatomical Structure Morphogenesis Organ Morphogenesis System Development Multicellular Organismal Development Tissue Development Platelet Degranulation Anatomical Structure Development Positive Regulation Of Cell Migration Bone Development Developmental Process Positive Regulation Of Cell Motility Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Growth Plate Cartilage Development Response To Wounding Extracellular Matrix Disassembly Organ Development Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Cellular Response To Growth Factor Stimulus Blood Coagulation Regulation Of Body Fluid Levels Wound Healing Hemostasis Response To Growth Factor Locomotion Collagen Catabolic Process Endochondral Bone Growth Regulation Of Epithelial Cell Migration Collagen Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Cartilage Development Involved In Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Response To External Stimulus Regulation Of Cell Migration Organ Growth Platelet Activation Regulation Of Cell Motility Positive Regulation Of Blood Vessel Endothelial Cell Migration Growth Positive Regulation Of Endothelial Cell Migration Regulation Of Locomotion Bone Morphogenesis
Tagcloud ?		abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs	ablated alcian alizarin bones brdu cartilage chondrocyte chondrocytes chondrodysplasia collagens dysregulated endochondral flox histomorphometrically hyperactivation hypertrophic ihh ire1 microdissected mineralization ossification plate rays shortening stains xbp1 xbp1cartdeltaex2 xbp1flox zones
Tagcloud (Difference) ?		abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs	ablated alcian alizarin bones brdu cartilage chondrocyte chondrocytes chondrodysplasia collagens dysregulated endochondral flox histomorphometrically hyperactivation hypertrophic ihh ire1 microdissected mineralization ossification plate rays shortening stains xbp1 xbp1cartdeltaex2 xbp1flox zones
Tagcloud (Intersection) ?