COL2A1 and COL9A3

Number of citations of the paper that reports this interaction (PMID 11724554)
4

Data Source:
HPRD (in vivo)

		COL2A1	COL9A3
Gene Name		collagen, type II, alpha 1	collagen, type IX, alpha 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type II Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix	Extracellular Region Proteinaceous Extracellular Matrix Collagen Type IX Trimer Endoplasmic Reticulum Lumen
	Molecular Function	Extracellular Matrix Structural Constituent Conferring Tensile Strength Identical Protein Binding Metal Ion Binding Platelet-derived Growth Factor Binding	Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Skeletal System Development Cartilage Condensation Tissue Homeostasis Endochondral Ossification Chondrocyte Differentiation Heart Morphogenesis Proteoglycan Metabolic Process Axon Guidance Central Nervous System Development Visual Perception Sensory Perception Of Sound Regulation Of Gene Expression Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Fibril Organization Collagen Catabolic Process Notochord Development Inner Ear Morphogenesis Cartilage Development Palate Development Limb Bud Formation Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Otic Vesicle Development Cellular Response To BMP Stimulus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Axon Guidance Male Gonad Development Female Gonad Development Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth	Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Degradation of the extracellular matrix ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: ANXA5 BGN BMP2 C1QA CHAD COL6A1 COL9A1 COL9A2 COL9A3 COMP DDR1 FGF7 FN1 HTRA1 HYAL1 ITGA2B LOXL4 MAG MATN1 MMP1 MMP13 PCOLCE PDGFA PDGFB PDIA2 PKD1 PRELP RELA SPARC TGFB1 TGFBI THBS1 TNFRSF10A	3 interactors: COL2A1 EGFR MAG
Entrez ID		1280	1299
HPRD ID		00361	00374
Ensembl ID		ENSG00000139219	ENSG00000092758
Uniprot IDs		P02458	Q14050
PDB IDs		1U5M 2FSE 2SEB
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Connective Tissue Development Cartilage Development Skeletal System Development Anatomical Structure Morphogenesis Organ Morphogenesis System Development Multicellular Organismal Development Tissue Development Platelet Degranulation Anatomical Structure Development Positive Regulation Of Cell Migration Bone Development Developmental Process Positive Regulation Of Cell Motility Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Growth Plate Cartilage Development Response To Wounding Extracellular Matrix Disassembly Organ Development Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Cellular Response To Growth Factor Stimulus Blood Coagulation Regulation Of Body Fluid Levels Wound Healing Hemostasis Response To Growth Factor Locomotion Collagen Catabolic Process Endochondral Bone Growth Regulation Of Epithelial Cell Migration Collagen Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Cartilage Development Involved In Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Response To External Stimulus Regulation Of Cell Migration Organ Growth Platelet Activation Regulation Of Cell Motility Positive Regulation Of Blood Vessel Endothelial Cell Migration Growth Positive Regulation Of Endothelial Cell Migration Regulation Of Locomotion Bone Morphogenesis	Cellular Response To Growth Factor Stimulus Response To Growth Factor Central Nervous System Development Alkanesulfonate Metabolic Process Locomotion Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Neurotrophin TRK Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Neurotrophin Signaling Pathway Generation Of Neurons Neurogenesis Ossification Activation Of Phospholipase A2 Activity Cellular Response To Organic Substance Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Response To Hydroxyisoflavone Axon Guidance Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Nervous System Development Limb Bud Formation Positive Regulation Of Catenin Import Into Nucleus Response To Organic Substance Embryonic Organ Development Regulation Of Phospholipase A2 Activity Axonogenesis Regulation Of Superoxide Anion Generation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Sensory Organ Development Magnesium Ion Homeostasis Chemotaxis Otic Vesicle Development Organ Development Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Estradiol Stimulus Embryonic Skeletal Joint Morphogenesis Protein Insertion Into Membrane Astrocyte Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Cell Morphogenesis Involved In Differentiation Embryonic Skeletal Joint Development Notochord Development Regulation Of Catenin Import Into Nucleus Cellular Response To Epidermal Growth Factor Stimulus
Tagcloud ?		ablated alcian alizarin bones brdu cartilage chondrocyte chondrocytes chondrodysplasia collagens dysregulated endochondral flox histomorphometrically hyperactivation hypertrophic ihh ire1 microdissected mineralization ossification plate rays shortening stains xbp1 xbp1cartdeltaex2 xbp1flox zones	acc adenoid aetiology bbc constitutes driver drivers foxa1 gpm6b insidious lacks massive mel metastasise metastasises mia myoepithelial neuroblastomaand oestrogen recur ropn1 ropn1b segregated shares signatures silico sox10 trim2 visualisation
Tagcloud (Difference) ?		ablated alcian alizarin bones brdu cartilage chondrocyte chondrocytes chondrodysplasia collagens dysregulated endochondral flox histomorphometrically hyperactivation hypertrophic ihh ire1 microdissected mineralization ossification plate rays shortening stains xbp1 xbp1cartdeltaex2 xbp1flox zones	acc adenoid aetiology bbc constitutes driver drivers foxa1 gpm6b insidious lacks massive mel metastasise metastasises mia myoepithelial neuroblastomaand oestrogen recur ropn1 ropn1b segregated shares signatures silico sox10 trim2 visualisation
Tagcloud (Intersection) ?