MAG and COL1A1

Number of citations of the paper that reports this interaction (PMID 2446864)
8

Data Source:
BioGRID (pull down)

		MAG	COL1A1
Gene Name		myelin associated glycoprotein	collagen, type I, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Paranode Region Of Axon Schmidt-Lanterman Incisure	Extracellular Region Collagen Type I Trimer Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Secretory Granule Extracellular Matrix
	Molecular Function	Carbohydrate Binding	Extracellular Matrix Structural Constituent Protein Binding Identical Protein Binding Metal Ion Binding Platelet-derived Growth Factor Binding
	Biological Process	Cell Adhesion Blood Coagulation Substantia Nigra Development Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis Leukocyte Migration	Skeletal System Development Blood Vessel Development Osteoblast Differentiation Intramembranous Ossification Endochondral Ossification Receptor-mediated Endocytosis Blood Coagulation Visual Perception Sensory Perception Of Sound Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cell-substrate Adhesion Protein Transport Extracellular Matrix Disassembly Platelet Activation Extracellular Matrix Organization Collagen Fibril Organization Positive Regulation Of Cell Migration Collagen Catabolic Process Response To Corticosteroid Response To Estradiol Collagen Biosynthetic Process Protein Localization To Nucleus Tooth Mineralization Response To Drug Response To Hydrogen Peroxide Response To Peptide Hormone Skin Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Tooth Eruption Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development Leukocyte Migration Response To CAMP Response To Hyperoxia Face Morphogenesis Bone Trabecula Formation Cartilage Development Involved In Endochondral Bone Morphogenesis Protein Heterotrimerization Cellular Response To Amino Acid Stimulus Cellular Response To Mechanical Stimulus Cellular Response To Retinoic Acid Cellular Response To Vitamin E Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Fluoride
Pathways		Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling Basigin interactions Cell surface interactions at the vascular wall	Platelet Adhesion to exposed collagen Collagen formation Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Cell surface interactions at the vascular wall Syndecan interactions Crosslinking of collagen fibrils ECM proteoglycans GPVI-mediated activation cascade Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Platelet activation, signaling and aggregation Scavenging by Class A Receptors
Drugs			Collagenase
Diseases
GWAS			Breast cancer ( 17903305) Response to taxane treatment (docetaxel) ( 23006423)
Protein-Protein Interactions		18 interactors: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R	37 interactors: ACHE ATP13A2 BARD1 BGN BMP1 BRCA1 CAPN1 CD36 CD44 CD93 COL7A1 DCN DDR2 FGF7 FN1 HTRA1 IGFBP3 ITGA2 ITGA5 MAG MATN2 MMP2 MMP9 NID1 NID2 P4HB PAK1 PDGFA PDGFB PKD1 PRELP SPARC TGFBI THBS1 TMPRSS6 TXN VWF
Entrez ID		4099	1277
HPRD ID		01160	00362
Ensembl ID		ENSG00000105695	ENSG00000108821
Uniprot IDs		P20916 Q53ES7	P02452
PDB IDs			1Q7D 2LLP 3EJH 3GXE
Enriched GO Terms of Interacting Partners?		Axon Development Cell Morphogenesis Involved In Differentiation Axonogenesis Extracellular Matrix Disassembly Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Generation Of Neurons Collagen Catabolic Process Neuron Projection Morphogenesis Neurogenesis Neuron Development Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Cell Morphogenesis Multicellular Organismal Metabolic Process Axon Guidance Neuron Differentiation Cell Projection Morphogenesis Cell Projection Organization Cell Part Morphogenesis Nervous System Development Cell Development Extracellular Matrix Organization Extracellular Structure Organization Movement Of Cell Or Subcellular Component Cell Differentiation Chemotaxis Locomotion Anatomical Structure Morphogenesis System Development Multicellular Organismal Development Anatomical Structure Development Response To External Stimulus Developmental Process Regulation Of Cell Development Regulation Of Neurogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Differentiation Regulation Of Neuron Differentiation Regulation Of Axonogenesis Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Organ Development Response To Stimulus Regulation Of Neuron Projection Development Central Nervous System Development Platelet Activation Regulation Of Cell Projection Organization Head Development Tissue Development	Extracellular Matrix Organization Extracellular Structure Organization Response To Wounding Extracellular Matrix Disassembly Wound Healing Multicellular Organismal Development Cell Adhesion Anatomical Structure Development Tissue Development Platelet Degranulation Developmental Process System Development Blood Coagulation Hemostasis Anatomical Structure Morphogenesis Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Regulation Of Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Protein Metabolic Process Regulation Of Locomotion Regulation Of Cellular Amino Acid Metabolic Process Response To Stress Regulation Of Cellular Component Movement Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Body Fluid Levels Regulation Of Cell Migration Cell-substrate Adhesion Regulation Of Epithelial Cell Migration Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Phosphorylation Endodermal Cell Differentiation Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Phosphorylation Skeletal System Development Regulation Of Cellular Protein Metabolic Process Organ Development Blood Vessel Morphogenesis Regulation Of Phosphorus Metabolic Process Platelet Activation Organ Morphogenesis Locomotion Endoderm Formation Angiogenesis Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Exocytosis
Tagcloud ?		abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs	archive bcl6 cancerous cebpb checked cufflinks david deg degs downloaded exph5 fastqc hg19 msx2 noiseq paracancerous ppp2r2c read samtools sox4 srp009386 tophat totally transfa trp53 uniquely v1 vcftools
Tagcloud (Difference) ?		abstract anhydrase bilayer brains carbonic cnpase coated compact concentrated edema enriched enrichment fractions gray matter myelin paranodal periaxolemmal plasmolipin prompted sevenfold tet tin triethyl vesicle vesicles virtually wmcv wmcvs	archive bcl6 cancerous cebpb checked cufflinks david deg degs downloaded exph5 fastqc hg19 msx2 noiseq paracancerous ppp2r2c read samtools sox4 srp009386 tophat totally transfa trp53 uniquely v1 vcftools
Tagcloud (Intersection) ?