MAG and COL9A1

Number of citations: 56 (PubMedID 2446864)
Data Source: HPRD (in vivo)

		MAG	COL9A1
Name		myelin associated glycoprotein	collagen type IX alpha 1 chain
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Paranode Region Of Axon Myelin Sheath Adaxonal Region Myelin Sheath Compact Myelin Schmidt-Lanterman Incisure Membrane Raft Mesaxon	Extracellular Region Collagen Trimer Collagen Type IX Trimer Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Signaling Receptor Binding Lipid Binding Protein Kinase Binding Carbohydrate Binding Sialic Acid Binding Protein Homodimerization Activity Ganglioside GT1b Binding	Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Carbohydrate Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Cell Adhesion Nervous System Development Negative Regulation Of Neuron Projection Development Transmission Of Nerve Impulse Substantia Nigra Development Central Nervous System Myelination Negative Regulation Of Axon Extension Axon Regeneration Positive Regulation Of Myelination Central Nervous System Myelin Formation Myelination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Cellular Response To Mechanical Stimulus Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Animal Organ Morphogenesis
Pathways		Axonal growth inhibition (RHOA activation) Basigin interactions EGR2 and SOX10-mediated initiation of Schwann cell myelination	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: RIMS1
Interacting Genes		18 interacting genes: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R	4 interacting genes: CFTR COMP FN1 MAG
Entrez ID		4099	1297
HPRD ID		01160	00367
Ensembl ID		ENSG00000105695	ENSG00000112280
Uniprot IDs		P20916 Q53ES7	A0A804HIB6 P20849
PDB IDs		Not available	2UUR 5CTD 5CTI 5CVA 5CVB
GO Terms Enriched among Interactors		Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Platelet-derived Growth Factor Binding Endoplasmic Reticulum Lumen Extracellular Matrix Fibrillar Collagen Trimer Basement Membrane Collagen Type IX Trimer Extracellular Matrix Structural Constituent Anatomical Structure Morphogenesis Skin Development Extracellular Matrix Organization Extracellular Structure Organization Collagen Fibril Organization System Development Cellular Response To Amino Acid Stimulus Protease Binding Extracellular Region Response To Amino Acid Cellular Response To Amyloid-beta Regulation Of Dendritic Spine Maintenance Developmental Process Proteoglycan Binding Regulation Of Postsynapse Organization Perikaryon Response To Amyloid-beta Animal Organ Morphogenesis Response To Mechanical Stimulus Cartilage Development Basement Membrane Organization Type 5 Metabotropic Glutamate Receptor Binding Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Growth Factor Receptor Binding Response To Xenobiotic Stimulus Collagen Type XI Trimer Negative Regulation Of Dendritic Spine Maintenance Neuron Projection Organization Regulation Of Synapse Organization Growth Cone Integrin Binding Response To Growth Factor Blood Vessel Development Central Nervous System Development Sensory Perception Of Mechanical Stimulus Nervous System Process Heparin Binding Homeostatic Process Limb Joint Morphogenesis Cellular Developmental Process	Proteoglycan Binding Vesicle Docking Involved In Exocytosis Regulation Of Developmental Process Regulation Of Developmental Growth Regulation Of Multicellular Organismal Process Vesicle Docking Collagen Binding Regulation Of Cell Growth Positive Regulation Of Developmental Process Regulation Of Multicellular Organismal Development Organelle Localization By Membrane Tethering Regulation Of Axon Extension Membrane Docking Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protease Binding Regulation Of Growth Extracellular Matrix Structural Constituent Regulation Of Nervous System Process Positive Regulation Of Anion Channel Activity Mesaxon Positive Regulation Of Monoatomic Anion Transport Heparin Binding Integrin Binding Positive Regulation Of Cell Growth Negative Regulation Of Monocyte Activation Regulation Of Axonogenesis Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Ganglioside GT1b Binding Positive Regulation Of Developmental Growth Regulation Of Exocytosis Positive Regulation Of Enamel Mineralization Anatomical Structure Formation Involved In Morphogenesis Cell Adhesion Tendon Development Cartilage Homeostasis Calcium-independent Cell-matrix Adhesion Regulation Of Anatomical Structure Morphogenesis Compact Myelin Nervous System Process Transepithelial Water Transport Response To Wounding Myelin Sheath Adaxonal Region Acrosomal Vesicle Exocytosis Positive Regulation Of Tooth Mineralization Cellular Component Assembly Positive Regulation Of Neurogenesis Neural Crest Cell Migration Involved In Autonomic Nervous System Development Central Nervous System Myelin Formation